The cuts, part of the White House’s “reduction in force” plan, were expected to effectively shutter or downsize multiple departments at the Centers for Disease Control and Prevention and other health agencies, potentially jeopardizing public health efforts.

HHS oversees 13 agencies, including the CDC, the Food and Drug Administration and the National Institutes of Health.

HHS said Thursday that 28 divisions in the health department contain “redundant units,” and that the restructuring plan will consolidate them into 15 divisions.

“We will eliminate an entire alphabet soup of departments, while preserving their core functions by merging them into a new organization called the Administration for Healthy America or AHA,” HHS Secretary Robert F. Kennedy Jr. said in a post on X.

Among the divisions being eliminated or reduced at the CDC, HHS said, are those focused on global health, domestic HIV prevention and prevention from injury, such as gun violence.

In total, the CDC will decrease its workforce by about 2,400 employees, said Andrew Nixon, a senior spokesperson for HHS. The administration will also move will also move the Administration for Strategic Preparedness and Response, which manages the nation's emergency stockpile, from HHS to CDC, he said.

The administration also will also make cuts to divisions at other agencies tasked with responding to approving new drugs, providing health insurance and responding to infectious disease outbreaks.

The FDA will decrease its workforce by about 3,500 full-time employees; the NIH headcount will be reduced by 1,200 employees; and the Centers for Medicare and Medicaid Services will lose about 300 workers.

Nixon said the reorganization of CMS will not impact Medicare and Medicaid services.

The cuts were separate from earlier attempts by government officials to fire thousands of probationary employees at the CDC and other federal agencies. Two federal judges have since ordered the temporary reinstatement of many of those affected workers.

Federal health officials had previously said they planned to shift responsibilities from some eliminated departments to other parts of HHS.

For example, the Trump administration was considering a plan to move the responsibilities of CDC’s Division on HIV Prevention over to the Health Resources and Services Administration, which does its own HIV work under The Ryan White HIV/AIDS program.

However, HRSA is primarily focused on the treatment of HIV rather than preventing it, leaving some HIV advocates concerned it could drive back progress on prevention.

It was unclear Thursday whether that was still the administration's plan. A spokesperson for HHS did not immediately respond to a request for additional comment.

Much of the responsibility for the newly downsized agencies at the CDC will likely be left to Susan Monarez, Trump’s pick to lead the agency and its current acting director.

Earlier this month, The Associated Press reported that five CDC division leaders resigned as the agency prepared for cuts.