Warning: Grapefruit can interact with drugs, such as decreasing the effectiveness of estradiol, making Oxycodone last longer, increasing blood levels when on Viagra, and much more.
Grapefruit inhibits multiple enzymes in the small intestine, most notably CYP3A4. CYP3A4 is involved in the breaking down of a lot of drugs, so when it's inhibited Oxycodone becomes inactive slower, and estradiol won't break down all the way into estrogen. Drugs that are affected by grapefruit will often have warnings on their packaging
Personally, I like putting just a little bit of salt on my grapefruit, to counteract the bitter flavor. Dumping sugar on it doesn't help. Grapefruits are about half as sour as lemons, since they have half the citric acid content.
Grapefruits were accidentally created as a cross between the sweet orange and the pomelo, in Barbados. Those fruits originate from Asia, but were brought to the Caribbean in the 17th century. Since it's parent fruits are native to Asia, it grows well in Asia too.
and 
(China and Vietnam) are the two largest producers of Grapefruits, producing collectively 6.3 million tons out of the 9.8 million tons of worldwide production.
The painting was made by Robert Papp, who has a website here: https://robertpapp.com/. I don't really know anything about the guy.
The lemon things with all of the recipes was really cool, but to be honest I just like grapefruit raw, cut in half and ate with a spoon.
Join our public Matrix server!
https://matrix.to//#/#tracha-space:transfem.dev
https://rentry.co/tracha#tracha-rooms
As a reminder, please do not discuss current struggle sessions in the mega. We want this to be a little oasis for all of us and the best way to do that is not to feed into existing conflict on the site.
Also, be sure to properly give content warnings and put sensitive subjects behind proper spoiler tags. It's for the mental health of not just your comrades, but yourself as well.
Here is a screenshot of where to find the spoiler button.
___
Estradiol regardless of form gets metabolized by a specific liver enzyme. Some specific part of grapefruit, for reasons known only to god, interferes with that enzyme. So it will mess with your levels. If you have a grapefruit every once in a while, like once a month or less, youll probably be fine.
CBD also interferes with that liver enzyme but since most people stick with whatever their regiment of weed intake before and after HRT, it's kind of baked in - but technically we should be advising no CBD and likely no cannabis in general, but imagine that struggle yeesh. Grapefruit, on the other hand, people don't eat it on the regular and some meds go through the same liver enzyme pathway. So generally, if you are taking any med that is affected by grapefruit you should just skip the grapefruit.
most people don't eat it on the regular
Thanks for the heads up tho! I honestly don't know or care that much about my levels so long as I don't completely throw them out of whack to a dangerous degree haha
the cbd thing is interesting too but also most of the weed you can buy is so low cbd these days I wonder how big the effect is
oops I take CBD every night to help me sleep, maybe not enough to affect anything though?
If you take it every night you'll be fine