Earplugs. Put them in as soon as you scan your boarding pass and are waiting in the jetway to get on the plane. Nothing that is said to you after that point will be important until you're off the plane; and if it is, you can just take out one earplug and say "say again?" You can avoid most of the annoyance of in-flight announcements and advertisements, screaming babies, and jet engines.
Drugstores. Your destination probably has them. You don't need to pack any toiletries that you can easily obtain in one. If you are flying to New York City, you do not need to bring toothpaste with you; they have toothpaste in New York City, and you can just buy it in the Duane Reade shop that's a block from your hotel. They have toothpaste in San Juan and Paris too. In any tropical destination, they have sunscreen there — and the sunscreen they sell there is actually safe for the coral reefs.
Water bottles. Many major airports have stations for refilling water bottles after you clear security. You can take an empty water bottle, fill it up, and carry it on the airplane.
Masks. In the old days before COVID, nobody wore masks in airports, and lots of people got colds or flu when traveling. These days, you can wear a mask and people may think you're weird but you are less likely to pick up random respiratory diseases. I regularly wear a standard 3M N95 mask in American airports and no longer get the sniffles every time I travel.