Trans Megathread from June 8th to June 14th
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I forgot that it's my mega week so no big info dump this time. Instead I bring a question: how do you practice gender self-care? Do you have any activities or rituals that make you feel more comfortable in your gender? Painting my nails and taking care of my hair are the most consistent ones. These shouldn't even be considered gendered activities by society, but I missed out on having long hair and painted nails when I was younger because of my assigned gender, so doing them now feels validating and gives me confidence.
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this post was submitted on 08 Jun 2026
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You should get labs to verify your current levels. There is a lot of variation in pharmacogenomics, everyones liver is different (I remember one study showing 70% variation between siblings in pharmakinetics of some drug).
The idea of higher E levels to mimic puberty is interesting, I will say when I upped my doses and started having the intense emotional side of puberty - I backed off lol. I get that you wanna make it go faster but Im skeptical its much any faster than current dose plus time. I would be curious what the diy femme hrt people think of it, theres not tons of studies but they do some research.
400 sounds fine for what its worth as well if thats your personal target.
I know, I am hoping to be able to get blood work soonish. Do injectibles go through your liver? I thought that was one advantage over E pills.
I mean I do, but someone had suggested it multiple times to me so I thought it was something I should investigate/ask others opinions on.
Okay cool, glad you think that range is okay though, I trust your view on that
First pass oral means it goes through your liver, is highly metabolized by it, then goes systemic. Parenteral routes like injections skip the first pass, but eventually your body is gonna start cleaning stuff out cause thats what it does. Short of a clone organ or whatever that produces estrogen/progesterone on its own, youll always be clearing out whatever you put in instead of homeostasis.