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What are your gays thoughts on me upping my E from 4mg een weekly to 6mg? https://estrannai.se/#imt0__cu,4,7,2-cu,6,7,2
Someone has been suggesting this to me, that raising E levels would more closely mimic cis puberty. Which I don't hate as an approach, I'm just not sure if I need to I guess. The biggest drawback I see is using my vials faster. idk, anyone have thoughts?
8 months hrt no labs.
You should get labs to verify your current levels. There is a lot of variation in pharmacogenomics, everyones liver is different (I remember one study showing 70% variation between siblings in pharmakinetics of some drug).
The idea of higher E levels to mimic puberty is interesting, I will say when I upped my doses and started having the intense emotional side of puberty - I backed off lol. I get that you wanna make it go faster but Im skeptical its much any faster than current dose plus time. I would be curious what the diy femme hrt people think of it, theres not tons of studies but they do some research.
400 sounds fine for what its worth as well if thats your personal target.
You guys keep giving me ideas of stuff to try to study. I need to become a pharmacist and researcher so much. Hopefully this year I'll start it, hopefully in a public university.
I know, I am hoping to be able to get blood work soonish. Do injectibles go through your liver? I thought that was one advantage over E pills.
I mean I do, but someone had suggested it multiple times to me so I thought it was something I should investigate/ask others opinions on.
Okay cool, glad you think that range is okay though, I trust your view on that
First pass oral means it goes through your liver, is highly metabolized by it, then goes systemic. Parenteral routes like injections skip the first pass, but eventually your body is gonna start cleaning stuff out cause thats what it does. Short of a clone organ or whatever that produces estrogen/progesterone on its own, youll always be clearing out whatever you put in instead of homeostasis.
You should get labs first, then labs after 6 weeks on the new dose to see the difference, if you choose to go down that route. And yeah, you'll go through vials much faster. FWIW, I've been taking 7mg EEn and got my labs done for the first time in forever and my E was at 528pg/mL at trough. Definitely going to dial it back to 5mg going forward. I'm way past hitting my numbers and would rather have my vials last longer.
Probably a waste of estrogen without a lab to indicate otherwise.
I definitely agree that doing blood tests is a good idea. But also Estrogen's never wasted if you're putting it in your body IMO