this post was submitted on 19 Jul 2023
22 points (100.0% liked)

News

7 readers
5 users here now

Breaking news and current events worldwide.

founded 1 year ago
 

A team led by famed Harvard Medical School anti-aging researcher David Sinclair has just published a paper that shows a mix of chemicals are capable of reversing cellular aging...

top 13 comments
sorted by: hot top controversial new old
[–] [email protected] 22 points 1 year ago* (last edited 1 year ago) (4 children)

I look forward to having a class of rich people who will never die with the rest of us being considered expendable /s

[–] [email protected] 6 points 1 year ago (1 children)

Literally a sub plot of the red mars series.

[–] [email protected] 5 points 1 year ago

Also a plot on Altered Carbon. “Meths”, short for methuselahs, rule the world. You get a new body if you can afford it otherwise you get what we give you.

[–] [email protected] 5 points 1 year ago

Remember not aging doesn't necessarily mean immortal.

https://www.wikihow.com/Build-a-Gallows

[–] [email protected] 4 points 1 year ago (1 children)

Great, they'll live to see the consequences of climate change and slowly die anyway

[–] [email protected] 5 points 1 year ago (1 children)

They will move to subterranean refuges and keep their everlasting bodies connected to the metaverse.

[–] [email protected] 2 points 1 year ago* (last edited 1 year ago) (1 children)

So... this is what hell was referring to all along?

  • evil people: check
  • underground: check
  • everlasting: check
  • ~~metaverse~~ torment: check
[–] [email protected] 1 points 1 year ago

I mean, if I had to spend some hundred years in that fun-less wii loby controlled by the Zuck...

Which is a great plot for Black Mirror. Netflix, call me.

[–] [email protected] 1 points 1 year ago

Oh yes, I really look forward to a future where people like Trump or Rupert Murdock live forever.

[–] [email protected] 5 points 1 year ago

Abstract

A hallmark of eukaryotic aging is a loss of epigenetic information, a process that can be reversed. We have previously shown that the ectopic induction of the Yamanaka factors OCT4, SOX2, and KLF4 (OSK) in mammals can restore youthful DNA methylation patterns, transcript profiles, and tissue function, without erasing cellular identity, a process that requires active DNA demethylation. To screen for molecules that reverse cellular aging and rejuvenate human cells without altering the genome, we developed high-throughput cell-based assays that distinguish young from old and senescent cells, including transcription-based aging clocks and a real-time nucleocytoplasmic compartmentalization (NCC) assay. We identify six chemical cocktails, which, in less than a week and without compromising cellular identity, restore a youthful genome-wide transcript profile and reverse transcriptomic age. Thus, rejuvenation by age reversal can be achieved, not only by genetic, but also chemical means.

https://www.aging-us.com/article/204896/text

[–] [email protected] 5 points 1 year ago

It’s Sinclair, stuff around him always gets overly-sensationalized, but skimming though the actual paper… damn, it looks surprisingly promising.

[–] [email protected] 2 points 1 year ago (1 children)

and surely everyone will benefit from this right? not just the rich? right?

[–] [email protected] 1 points 1 year ago

Depends on if you believe history, which shows technology always spreads, or Hollywood, which would have you believe in conspiracy theories.

load more comments
view more: next ›