24
submitted 4 days ago by Swaus01@piefed.social to c/adhd@lemmy.world

Interested primarily in hearing from people who've tried more than one type of ADHD Zmedication, to compare their experience under each one. Also interested in people who just know what various different med types are targetting.

I'm in titration for medikinet's Methylphenidate Hydrochloride and it doesn't seem so effective. Very little difference to how i behave on it versus off of it, it does heighten my sense of fun and make me focus in videogames for longer though. It does make talking to people and masking a lot easier, however. I'm wondering if i should ask to switch to another one.

top 13 comments
sorted by: hot top new old
[-] afaix@lemmy.world 7 points 4 days ago

Wellbutrin: felt easier to start tasks without waiting for motivation to hit, gave me headaches

Atomoxetine (Strattera): after a month felt a little less distracted, affected my mood and killed the sex drive, I was too irritable and had problems with relationships.

Methylphenidate (Ritalin): helped me stay awake and a bit less distracted, gave me a rash so I couldn’t take it longer or higher doses to see if taking more would make any difference

Lisdexamfetamine (Vyvanse): improved focus, kept me awake for 16 hours at a time, kills appetite, dries the throat, causes sweating, makes me want to go to the bathroom more often, makes me feel stressed a bit, tenses muscles in the head a bit too. The least worst out of them all so far, I’m trying to channel how I feel while on it to act more focused on the days when I’m not taking it, and it seems to help a bit.

Most difference for all of them I’ve noticed after I’ve stopped taking them, suddenly realizing that though while taking them it felt like they only helped a tiny bit, it was actually noticeably harder to do things without them.

Still, Lisdexamfetamine was the only one immediately noticeable, just need to watch myself and make sure to get more showers, remember to hydrate and to eat properly, to take it early in the morning and to force myself to sleep on time (didn’t learn how to do that yet though)

[-] Swaus01@piefed.social 2 points 3 days ago* (last edited 3 days ago)

Most difference for all of them I’ve noticed after I’ve stopped taking them, suddenly realizing that though while taking them it felt like they only helped a tiny bit, it was actually noticeably harder to do things without them.

I'm considering just going med-less for this reason. There were times in my life without medication when i was perfectly productive, e.g in teenagehood, and shortly before i started titration i feel like i got well into my productivity groove because i started implementing systems for keeping myself in check. Exactly like you say here, the meds feel like a small difference at the time and a big difference later - i don't want to convince myself that i need them to function at work.

Thank you for sharing these details

[-] DrakeAlbrecht@lemmy.world 8 points 4 days ago

I've been on Vyvanse, Adderal, and Strattera.

Vyvanse was helpful. I was able to hold the same job for four years, where before my focus was so poor I would rarely last a year. I'm trying to get my psychiatrist to prescribe it again. There were no noticeable side effects.

Adderal didn't have any noticeable side effects, but it wasn't as effective as Vyvanse.

Strattera gave me no benefit, but caused the worst constipation I've ever experienced. Even now, more than a decade later, I still say I'm "all Stratterad up" when I can't poop.

[-] Zarobi@aussie.zone 3 points 4 days ago

In my anecdotal experience, Vyvanse was great for a long time, but it slowly "built up" some kind of cardiac side effects, and after 2 years I was really suffering, no matter the dose. I've heard this isn't uncommon, which surprised me. I ended up in hospital a few times before they told me to stop taking it.

[-] Swaus01@piefed.social 2 points 3 days ago

I wonder if this happens with other meds as well. I don't want to take anything that'll do that to me

[-] Zarobi@aussie.zone 2 points 3 days ago

It's one of those things where simultaneously keep an eye on it but don't worry about it too much. Honestly I was an idiot because I just kept going to hospital without thinking maybe my medications are the problem lol. I just assumed that if it was fine after 3 months it'd be fine after 24 months. A lot of people have zero issues, I was just both unlucky and stupid

[-] AnarchistArtificer@slrpnk.net 3 points 3 days ago

Commenting to pin so I can reply more fully when less sleepy

[-] TheJesusaurus@piefed.ca 6 points 4 days ago

I'm on methyl whatever and I too don't find it to be terribly useful. I don't even find it makes masking any easier.

[-] Swaus01@piefed.social 3 points 3 days ago

I've really struggled to get this across to my psychiatrist because i said it didn't help my productivity (which is essentially the only reason why i wanted it) and he instead honed in on the fact it helped my social skills. I didn't know that was possible to achieve from drugs.

[-] crash_thepose@lemmy.ml 4 points 4 days ago* (last edited 4 days ago)

I'm on combo thing of Vyvanse and Adderall and everyday is just a gamble if I will feel exhausted all day or overwhelmed with anxiety... Or both.

[-] surewhynotlem@lemmy.world 4 points 4 days ago

Wellbutrin. I'm level. Just seems... Normal

[-] snooggums@piefed.world 4 points 4 days ago

Methylphenidate is awesome for me, but I need two ER pills to cover the whole day. It helps me remember enough small things to complete things and doesn't have side effects like the other meds I tried first.

It has been long enough I don't remember which other ones I tried, but they affected my mood and this one doesn't.

[-] thesohoriots@lemmy.world 3 points 4 days ago

I benefit most from the amphetamine/dextroamphetamine ones, which give me an energy boost (e.g. vyvanse, mixed salts). Methylphenidate ones (e.g. focalin, concerta) give me only focus and it feels like everything else slows down, making for some long and tired days. I can’t speak for the strattera/guanfacine/Qelbree type stuff. But essentially if one particular category of the three types works, that’s your lane.

this post was submitted on 01 Jul 2026
24 points (100.0% liked)

ADHD

13360 readers
58 users here now

A casual community for people with ADHD

Values:

Acceptance, Openness, Understanding, Equality, Reciprocity.

Rules:

Encouraged:

Relevant Lemmy communities:

Autism

ADHD Memes

Bipolar Disorder

Therapy

Mental Health

Neurodivergent Life Hacks

lemmy.world/c/adhd will happily promote other ND communities as long as said communities demonstrate that they share our values.

founded 3 years ago
MODERATORS