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[–] 86 points 3 months ago (8 children)

Getting a...

poop transplant.... monkey-typewriter

to cure my autism monkey-typewriter

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  • [–] 53 points 3 months ago (4 children)

    I still can't believe poop transplant is a real thing. It sounds like a shitpost

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  • [–] 19 points 3 months ago* (2 children)

    I would be okay with fixing my gastrointestinal issues and some of my cognitive struggles if I kept my cognitive differences.

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  • [–] 7 points 3 months ago

    thankfully I don't think that this sort of therapy would change everything about someone's cognition. We already know that autistic and ND brains have physical differences in their construction compared to neurotypical folks. We also knew that new structural differences may not be the entire story!

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  • [–] 65 points 3 months ago (4 children)

    This is funny because most autistic folks I know usually feel better when they put their shit into me.

    Like infodumping about special interests. Is that a joke? You can ban me if that's not a good joke.

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  • [–] 44 points 3 months ago (2 children)

    Shoving shit up my ass so I'll shut up about trains and touhou

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  • [–] 43 points 3 months ago (1 child)

    I was a little bit ready to read an article that was hacky and about "finding a cure" but it was instead about addressing health whole-sale and reducing things that relate to discomfort or difficulty. Very nice to see :) (unless I missed something, which is possible!)

    Hope the research can continue to help people live the life they want. The gut-brain neural pathway continues being one of the wildest things to read about. Sounds like psuedo-science at first but I feel like the studies that keep coming out on it are really solid and surprising.

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  • [–] 39 points 3 months ago (1 child)

    Where do I sign

    Where do I fkn sign I'm so tired of this

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    [–] 25 points 3 months ago (2 children)

    Has anyone tried the reverse?

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  • [–] 25 points 3 months ago (1 child)

    Bong hit transplants have a much higher success rate

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  • [–] 24 points 3 months ago* (2 children)

    If an author invented the concept of fecal transplants for a story, I'd think they were fetish worldbuilding

    Same goes for premarin (not because it's an HRT drug but because of its, uh, particular source)

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  • [–] 22 points 3 months ago
    [–] 21 points 3 months ago* (last edited 3 months ago) (5 children)

    I have heard parents say that changing diet helped their children with autism, though I would hardly call that a scientific study


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  • [–] 17 points 3 months ago (4 children)

    There's actually a bit of research on autism and diet. What I'm familiar with is sulforaphane (from broccoli, cabbage etc) showing an improvement in symptoms. This video talks about the causes that can impacted by diet, links to the studies referenced is under sources

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  • [–] 15 points 3 months ago*

    Fun fact: Two thirds of all scurvy cases occur in people diagnosed as autistic.

    I heard a lecturer say that with extreme deficiencies in juveniles you hope for autism as a "comorbidity" because that's harmless and then you have a cause.

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  • [–] 20 points 3 months ago

    Now I just want a T-shirt that says "Fecal Transplants for Autism" with a brown ribbon.

    It's just WTF enough to get people interested enough to ask a question, then BOOM! I hit them with science!

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  • [–] 19 points 3 months ago

    So you're telling me my problem isn't that i'm full of shit, it's that it's the wrong kind

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  • [–] 15 points 3 months ago (1 child)

    the comments on that article are abysmal, even more so then public comments on news articles usually are

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  • [–] 13 points 3 months ago* (1 child)

    For far too long, shit has only come out of the asshole. Until today, nobody was daring enough to ask, what if shit went into the asshole too? What if the asshole could function in duplex?

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    [–] 12 points 3 months ago

    to be honest gut microbiome and autism reminds me of andrew wakefield lmao

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  • [–] 11 points 3 months ago (2 children)

    I thought they'd already tried this? I know someone who did research about this like half a decade ago. I may look at the study tomorrow.

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  • [–] 18 points 3 months ago (1 child)

    Yes, it sais right at the beginning, that the original article was from 2019. But they updated and republished it, because they did new studies. This time placebo controlled, larger and longer. Previously, the initial reduction in symptoms was 24%, now they showed, that after two years it's 45%. Also, these are official clinical trials for FDA approval, so it's closer to be made available for the public now.

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  • [–] 6 points 3 months ago*

    Also most research is straight up non-reproducible and, even worse, produces the opposite result of the study when reproduced. So this could be quite groundbreaking stuff.

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  • [–] 9 points 3 months ago (1 child)

    Fucking awesome!!! I hope they get the funding they need for the next round of testing.

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  • [–] 9 points 3 months ago

    So pooping back and fourth forever is real

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  • [–] 8 points 3 months ago

    taking my shit pill to not be an autist brb

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  • [–] 5 points 3 months ago

    RFK jr is going to read this and suggest we do human centipede irl

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  • [–] 4 points 3 months ago (3 children)

    Could this mean that fecal transplants are generally useful? The mechanism it proposes is that microbial diversity helps with autism symptoms. Does the helping peter out when a person reaches typical microbial diversity, or could somebody with typical microbial diversity reap some benefits by increasing it from there? How far is a typical person from the theoretical peak microbial diversity where they have a population of pretty much every microbe that's in somebody's gut?

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  • [–] 7 points 3 months ago

    I guess it's more like 'having gut microbes that can help you digest the food you eat is helpful', and less pokemon collecting all the microbes that can grow in your gut. H. pylori can grow in your gut, but you probably don't want it.

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  • [–] 6 points 3 months ago

    generally useful in terms of autism or generally useful in other fields of medicine? because the latter is ABSOLUTELY true.

    I don't think it's really possible for there to be a peak diversity like you describe, though. changing your diet even slightly compared to your usual meals is enough to radically change the balance of organisms in your gut, and the reproductive time for most bacteria means spontaneous changes in DNA can change this balance within hours.

    this does make me think, that perhaps a dialectical approach to managing gut health would benefit those taking on research in gastrointestinal medicine.

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