Futurama

"If it's a lesson in love, watch out; I suffer from a very sexy learning disability. What do I call it, Kiff?"
―Zapp

"[Sigh] "Sexlexia""
―Kiff

I can wire anything directly into anything! I'M THE PROFESSOR!

I'll start my own amusement park with blackjack and hookers. In fact, forget the blackjack.

"Thanks to denial, I'm immortal!"

"What really killed the dinosaurs?" " ME!!! "

"But you're better than normal! You're abnormal!"

Tie between:

If anyone needs me, I'll be in the angry dome

angry muttering as the PES flies away

and

Well Susie, it isn't foreigners, it's global warming

Gwabu wabu?

Uh, sure...

I'll use the poor as a source of teeth for aquarium gravel

Not exactly an iconic line, but I love the delivery:

"Have you heard of the Monks of Deshuba?"

Fry: "I've... not heard of them."

Futurama's great for nerdy science gags, social satire, and pop culture spoofs, but its best jokes are always uniquely stupid twists of language like this.

"I'm going to remind Fry of his humanity, the way only a woman can."

"You're going to do his laundry?"

Edit - the one that had me literally rolling off the couch because I was laughing so hard was, "That just raises further questions!"

What makes a man turn neutral?

The one I use most often: "I've heard worse excuses to drink".

There's not a restaurant built that I can't fly - Zap Brannigan

Gundersons Nuts! They're Nut so good!

I'm Shocked. SHOCKED! well not that shocked.

Hey. Fry. Pizza going out. C'MON!

My lead pipe hurts.

“Take the deal, Fry! If there's a delicious cake, isn't it better to have one slice than none at all? Even if four other guys eat the other four slices, and they're all thrusting their sweaty naked bodies against the cake?”

"wooooooooo"

"What about what?" - Philip J Fry responding to the professor yelling WHAT in a tiny ship in Fry's ear when the professor and crew controlled tiny robot versions of themselves to sneak inside Fry's body

And Fry, you've got that brain thing!

• I already did!

I sublibed with obly tribial blain dabblage.

MY LEG FEELS FUNNY

...

MY LEG FEELS BETTER

I'm Scruffy, the janitor.

This isn't a productive area of discussion.

"Your mother!"

Robot house

I can't believe everybody's just ad-libbing!

I could do without these boobs flopping about