this post was submitted on 22 Sep 2024
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D-phenylalanine (enkephalinase inhibitor)

Interesting substance, its one of the few dextro (right-spinning optical isomer) amino acids that you can process or something.

I think its fascinating because its purportedly an ~~endorphin reuptake~~ enkephalinase inhibitor? or something so its potentially quasi-opioidergic. I'm not sold on the notion its legit but its definitely a provocative idea.

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[–] [email protected] 2 points 1 day ago

Leucine for dem gains

[–] [email protected] 17 points 1 day ago (1 children)

Glutamate is good to know about.

It’s the oldest intercellular signaling chemical in evolutionary history. Sponges use glutamate to communicate between cells, so it predates nervous systems.

It has tons of distinct meanings in the human body’s context, but mostly it means “fight or flight”. A state of excessive glutamate signaling, sometimes referred to as a “glutamate storm”, is associated with feelings of overwhelm and panic attacks.

It can be blocked from binding by a chemical called L-theanine, which occurs naturally in tea and can be bought in pills at supplement stores. Studies have shown that people who take L-theanine supplements experienced reduced beta wave amplitude and increased alpha wave amplitude.

In my own experience, L-theanine pills can basically nullify the “frozen” feeling I have with procrastinating on complex work, such as homework or software development, or even just complex decision-making.

In other words, it’s the most effective anti-procrastination substance I’ve ever encountered. This is compared with:

  • anti-anxiety meds like xanax
  • blood pressure meds like propranolol
  • more coffee
  • adderall
  • ritalin
  • cocaine
  • alcohol
  • antidepressants
  • microdosed LSD
  • microdosed psilocybin
  • pseudoephidrine
  • maca

… all taken at once. Not recommended

[–] [email protected] 2 points 1 day ago (1 children)

all taken at once

I beg your finest pardon. That’s my secret recipe to success.

+1 for L-theanine though, it’s one of my favorite supplements. Although, more than once I’ve had to explain to someone that it’s not a Spanish word (“el theanine”).

[–] [email protected] 1 points 16 hours ago

Of course. In Spanish it’s el teanino

[–] [email protected] 9 points 1 day ago (1 children)

MSG because it's delicious.

[–] [email protected] 2 points 1 day ago (1 children)

This feels like one of those "is water wet?" pseudo-paradoxes.

Is MSG actually tasty or does it make other things tasty while not actually being tasty itself?

[–] [email protected] 2 points 20 hours ago (1 children)

definitely A. Eat a big spoonful sometime.

[–] [email protected] 1 points 20 hours ago (1 children)

The video of the soon-to-be-very-disappointed kid eating a spoonful of drinking chocolate powder just played in my head. And oh, there goes a cinnamon challenge one as well.

I think I'll pass.

[–] [email protected] 2 points 20 hours ago

no, no. I promise you that it's delicious. it's like biting into a ball of miso.

[–] [email protected] 12 points 1 day ago* (last edited 1 day ago) (1 children)

Tryptophan. It is a biochemical precursor for important neurotransmitters, vitamins and hormones such as melatonin, serotonin, and niacin. There happens to be very high concentrations of it in milk and eggs, both of which I love a lot. It can have sedating effects and make you feel chilled out!

[–] [email protected] 3 points 1 day ago

I am a fan of tryptophan!

[–] [email protected] 8 points 1 day ago

Public schools and religious college failed me. I do not have a favorite amino acid.

[–] [email protected] 7 points 1 day ago

As a pirate, my favorite amino acid is arrrrr-genine 😁

[–] [email protected] 7 points 1 day ago

Glutamine makes mouths happy!

[–] [email protected] 9 points 1 day ago

Cysteine, because it makes proteins stable.

[–] [email protected] 7 points 1 day ago

I'm going with the canned Mom 'I love them all equally' response because I don't want any essential amino acid to feel scorned

[–] [email protected] 7 points 1 day ago (1 children)

Alanine. No baroque ornamentation, just the beauty of simplicity. A timeless classic.

[–] [email protected] 1 points 1 day ago

Also, when made of moly-mod it can stand up and looks like a giant robot.

[–] [email protected] 8 points 1 day ago (1 children)

Probably plain L-phenylalanine, since it's the precursor to phenethylamine, the body's natural amphetamine.

[–] [email protected] 2 points 1 day ago

Have you taken l- or dl-phenylalanine?

[–] [email protected] 4 points 1 day ago

https://youtu.be/Fn0jhDEtEGI

Because surf rock aliens with a theremin are awesome

[–] [email protected] 3 points 1 day ago

glycine. so if anyone is aware of cron there was a study which showd methionine restriction seemed to have a similar effect and a further study that glycine which helps eliminate glycine to do so as well as a supplement. Mouse studies though (not cron which has more data but the others are like one study each last I saw.)

[–] [email protected] 6 points 1 day ago (1 children)

Tryptophan because it helps you be happy and sleepy.

[–] [email protected] 4 points 1 day ago (1 children)

Is that what the brain makes after sex?

[–] [email protected] 2 points 1 day ago

I think you get it from eating turkey.

[–] [email protected] 6 points 1 day ago

Metionine, because everything starts of it.

[–] [email protected] 5 points 1 day ago (1 children)

Lysine, because ingen tried to use it to control dinosaur populations.

[–] [email protected] 1 points 1 day ago

I also give it to my cats for immune support

[–] [email protected] 3 points 1 day ago

Proline because it's kinky.