https://www.neurology.org/doi/10.1212/WNL.0000000000217363
This one proposes a mechanism for how it works
https://pmc.ncbi.nlm.nih.gov/articles/PMC8313851/
Low-Dose Naltrexone is cheap and there is evidence it helps some people a lot with CFS, maybe ask about that? It is naltrexone, but taken at very small dose it has what the researchers call a 'novel effect' that is sort of the opposite. I don't know that anything cures it but don't lose hope or think nothing can help. People are studying it.
