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This is talking about the population of immunocompromised people, eg, people on immunosuppressants. It is not saying that the entire population of America is immunocompromised
Here's the letter. I don't think I agree. I'd argue there's much less ambiguous language they could have used then.
As they did later on when speaking of doses of JYNNEOS.
That, and well, we are all pretty much immunocompromised at this point. Turns out multiple infections of a virus that attacks endothelial cells isn't a good idea.
I agree with teapot.
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"Population" just means "group of people with this particularity" in epidemiology, not "the american population." Nothing in the text you shared suggests america is immunocompromised
Regardless of what the letter says, it's a moot point. A year and a half later the general pop of the US is largely immunocompromised. Unless you're living under a rock, it's pretty obvious that we are living through a mass disabling event and humanity is on the path of mass immune dysregulation