We're not fast and don't have a lot of natural weaponry
We are pretty fast compared to a lot of animals, especially when it comes to speed over any significant distance. Only a few other animals (like wolves and horses) can beat us in a long-distance race. And we're especially good at maintaining speed over distance in high temperatures -- as the temperature rises, our advantage there increases.
And having two hands to grab and grapple with (as opposed to only a mouth) is also a pretty rare and special skill in the animal kingdom. Maybe not the most impressive 'natural weaponry', but still quite useful and something to be feared by other animals. Then there's our sheer size -- we're certainly not the biggest ever, but in the grand scheme of things, we're definitely on the larger end of the spectrum, which gives us an advantage over most animals out there.