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this post was submitted on 21 May 2026
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You're mostly correct, tho the bit about genetics (+++) and sex is a bellcurve meme... There's tons we don't know and a lot of it is a giant interconnected mesh of incredibly complex relationship we barely grasp with very little casual data, and just a tiny bit of epidemiological inference that we can almost try to reason from.
Can you explain further? I’m a biochemist / medical lab scientist, and between my studies in genetics, human sexuality, and endocrinology, it seems pretty well figured out. Between “normal” X/Y chromosomes, various chromosomal abnormalities (X, XXX, XXY, XYY, etc), and mutations like androgen insensitivity syndrome it seems there is significant causal data. Not sure if they’ve studied these with knockout mice but it’s well beyond inference at this point.
I’m not sealioning here, it has been like a decade since I was actively learning this stuff and I’m sure there have been more discoveries. In general though it seems like we know the genetics, we know the hormones and receptors involved, the developmental process and various maladies are known, etc.
Are you sure? I'm not.
For someone taking the trouble to disagree with "sex is more complicated than binary M/F" there sure are a lot of caveats to your argument.
That is absolutely not what I’m saying. I’m saying the biological processes that lead to intersex or otherwise “complicated” sex conditions are fairly well understood. Sex is much more complicated than just the M/F dichotomy, and the current scientific and medical understanding of sex supports this.
Those who deny that sex is more complicated than binary M/F are rejecting well established science.
I'm so sorry, I completely got the wrong end of the stick.
No worries, thanks for allowing me to explain and reading what I said. Online discussions can be difficult these days.
Too true, too true.
You should ignore that poster. They're not right in the head.
Nah, seems like they just misinterpreted what I was saying.