chapotraphouse

Was making a reference to Overlord: an overworked salaryman from near-future cyberpunk Japan wakes up in a fantasy world as his VRMMO player character (i.e., the skeleton in the pic), and alongside with the evil NPCs created by himself and his former guildmates (they were a guild dedicated to roleplaying evil grotesque monsters) proceed to take over the world using the power of fantasy violence. Because the MC and his NPCs are absurdly over-leveled compared to the fantasy world natives, the casualties are incredibly one-sided and genocidal.

The show's a bit above average compared with other isekai, as it balances out its shameless powerfantasy with some decent comedy of errors and quite some effort being put into the worldbuilding/power system. It has a fair amount of typical anime horniness though, though I think it's relatively tame compared to the lowest common denominator isekai slop.