From James Fadiman's book on microdosing:

To speak about “microdosing” cannabis (marijuana) is a misuse of the term. The mechanisms, biology, and effects of cannabis are unique, complex, and powerful, but it does not resemble microdosing substances nor does its use provide the same range of benefits. Microdosing specifically refers to taking very small amounts of a psychedelic on a specific schedule over a number of weeks. The same term applied to taking a little bit of cannabis has nothing to do with actual microdosing. The effects and benefits of cannabis are totally different from the effects of psychedelics. Cannabis—the whole plant and a number of its different alkaloids—has been used successfully as a medication for many conditions. Good books on “medical marijuana” are available.1 Cannabis acts on and through the endocannabinoid system and affects the brain, body, and whole being differently than substances like LSD and psilocybin. Cannabis generally impedes neuroplasticity rather than enhances it. Brumback et al. (2016) conclude that “THC appears to block synaptic plasticity and neurogenesis”—the exact opposite of microdosing’s effects. Conor Murray’s 2024 research, discussed here, showed that LSD increased neural complexity, but THC did not. Cannabis is generally not taken with any standard protocol (days on/days off). People report “microdosing” cannabis throughout the day. None of this is microdosing. Moreover, THC is fat soluble and stores in the body’s fatty tissues and is detectable weeks after one stops using it. LSD and psilocybin are gone from the body within a day or so. Effective protocols are not possible because of this persistence. Conscious use of very small amounts of cannabis can be a rewarding experience or valuable practice, but it’s not microdosing.

I was wondering what would be the use of smaller doses of THC, like 1-4mg, maybe balanced with CBD, I am completely out of the topic of medical marijuana but seeing the improvements it did on me on a casual trial, I was wondering if any of you knew more about this!

Every atp command returns an avalanche of errors, I freed up some space but the package management stuff seems gone and I can't seem to fix it. Should I fresh install?

SOLUTION: Okay first of all thanks to all the people who replied to me and pointed me to the right direction, the issue was I was having full disk space and missing a few apt libraries which prevented the commands to run succesfully. I solved by freeing up some space, chrooting inside my corrupted environment from a live USB (there's plenty of guides online on how to do this correctly), I downloaded (from debian package search) and installed manually with dpkg a few packages: apt-transport-https, curl, and libnettle8t64 which apt-transport-https required and which was the one actually solving the problem. After that apt --fix-broken install could run succesfully and every further apt command worked without issues, upgraded the system and now it is booting fine! Again, thank you so much @mumblerfish@lemmy.world, @utopiah@lemmy.ml @hendrik@palaver.p3x.de, @ThanksForAllTheFish@sh.itjust.works, @BassTurd@lemmy.world, @IsoKiero@sopuli.xyz !

For some of them I kind of lost access so I would need to write emails to instagram or whatever, for others I would need to remember and to access to each one of them and delete them.

The hardest would be gmail with people having my contacts from like 10 years ago..

After spending 200$ for a supposedly premium Philips blender which broke in less than one year after having been sent to assistance, having parts replaced and broken again, been repaired by me and after I spent thousands of swear and curses, I am really this ' ' close to smashing it with an hammer and crucifying it to scare the other Philips products away from my kitchen.

Since those were 200$ wasted, and my parents and grandparents kitchen stuff worked sometimes for 30 years before breaking, where can I get my grandparents gear? Should I just resort to smashing vegetables and fruits by hand with stones?

Hi! I stumbled upn this: https://www.funkwhale.audio/

It is an amazing idea! Are there similar software you guys use? Is this the only currently federated music platform?

I want to take it as a tool for reading/writing/studying and super basic browsing. My phone just broke, chat control just got approved and I'm sick of proprietary shit: I decided I'm not gonna buy anything which doesn't hold free software anymore.

I love e-ink and I love Linux, but how usable is the pinenote with Linux? How hard is the install process? Can an average Linux user/self hoster use it daily? How's battery? Couldn't find many reviews online..

The shitty/distracting web run on ads, so why not making a search engine which index based on that? You would have an experience similar to what was the internet originally: no corporate shit, no infinite scroll, just independent websites made to share real informations and real knowledge, and would still leave space for subscriptions or donations! And you could still use JS and avoid just using a text browser, making the occasional order from a website or navigating the fediverse!

Not an ADblock, the issue isn't ads, the issue is how the web is TAILORED towards ads, and how that makes shitty web.

Is there any tool which does that? The goal would be blocking/avoid indexing all websites connected somehow to ads, is this even something possible? I know it would block 90% of the web, but if that 10% is freedom, I want that freedom!

If you plan to offer a service tied to a website you make for your client, what are the advantages of self hosting compared to relying on third party services?

Static sites, CMS, newsletter, emails, form handling and more..

An easy example is forms: you can either use formspree or install one of the countless foss form handlers you can find online..

In my mind it's definitely cooler to offer all the services your client needs + you can also charge for them without having to pay for 5 different plans on other platforms, just your VPS or dedicated machine, more income and less expenses. But I see it can be hard to manage outages sometimes or issues that can come with self hosting.

It's offering a service vs being just a reseller.

My experience with self hosting stuff on my own (for my own use) so far has been quite good. I don't use containerization and I carefully config everything needed the first time, then I reverse proxy through cloudflare, after that I rarely have issues and if I have I simply rely on logs.

In my mind it doesn't seem too hard to install a couple of services and make accounts for my clients + fixing something not working every now and then.

My only concern with that is if one day I will want to stop being a developer, how will I handle the quantity of people relying on my server and everything I will hold.

Interested in your thoughts and experience about self hosting vs relying on third parts!

Let's say I want to bridge from WhatsApp or telegram to Matrix, have I gaibed something in terms of privacy? In which case would it make sense? Public group chats? Direct chats?