Is an osteoblast posting this? They hate constantly getting their hard work removed by osteoclasts.

Human animal cracker

I have one big bone right now. Hey, baby

After all, it's not btwohundredsix.

Smooth, efficient, and most of all, calm

Well that would just be a gingerbread man.

Oh, humans can have basically one bone.

They are horrible and agonizing conditions, perhaps similar to being slowly partially or totally mummified by your own body.

Ankylosing Spondylitis, Pfeiffer Syndrome, Klippel-Feil Syndrome, etc.

Imagine your bones all fusing together. You can't bend, or maybe walk, move your jaw, or maybe even breathe.

Why not none? Bones are a terrible affliction.

MONOBONE

The human body evolved for resilience: having a large number of bones provides redundancy, meaning that we can break many bones and still have at least one to spare.

It's also partially a vestigial trait, as our ancestors needed to do a lot of boning in order for the species to survive - nowadays we don't need to replenish our numbers as much.

I also vote for outside bone instead of inside bone.

Where would all the soft parts go?

If we had just one, it would be very hard to move.

I'm just one big boned

For one thing you couldn’t hear sounds or noises all that good withou free-floating inner ear bones

Yeah, we say bone not bany, what gives...

Sometimes I have 207 bones, wink wink

It would be a lot more painful when drinking BoneHurtingJuice

I went out skiing and broke my... Armbonehiplegneckskull thing

Off we’re only had one bone then dogs would need to be way bigger and probably wouldn’t be our friends.

Flexibility. If everything was a thick, rigid bone we would be far less agile.

Energy. I imagine maintaining bone density for thicker bones would require more food to be consumed.

Medical. Breaking bigger bones would be more traumatic and debilitating than breaking smaller bones.