EverQuest.

XCOM

The Yakuza series I guess? Granted I've only played zero, kiwami and kiwami 2, but it all seems to be completely sincere in its craziness. It doesn't appear to pretend to be anything more than it is.

I would have to go with the Panzer Dragoon trilogy on the Sega Saturn.

While the first title was, at its basics, a fairly simple on rails shooter it was more than the sum of its parts.

It had incredible art direction, a sweeping musical score, innovative world building and rock solid gameplay.

The second title built up on the first installment in every way to solidify it as one of the best titles of that generation.

Then came Panzer Dragoon Saga which evolved the series into a full blown JRPG that is still so unique and unlike anything else out there.

Team Andromeda's passion, dedication and innovation ensured each game was a new benchmark for Segas black box.

What I wouldn't do for a new installment by the original team.

It's weird that Deus Ex isn't in this thread yet. Such a well made game with quite a few prophetic moments.

Suikoden

A lot of good suggestions but my first thought was Final Fantasy X.

The Stick of Truth, obviously.

Semi-jokes aside, I am a bit sad that not a single person mentioned the first four Silent Hill games. The sheer influence that series had on video games as a whole, especially in the horror genre cannot be overstated. But I guess it is tricky with games because everyone has different tastes and interests. It is rare that games unite people the way lord of the rings did. Gaming is at once so broad and so niche.

Wolfenstein 3D

Imma go with SNES Mario kart. People still play it. Will continue to play it. It was genre defining. It's not changing ever static. Simply to start but complex to finish.

Minecraft. Star Fox 64. Pokemon Stadium.

The ArmA series by Bohemia Interactive.