An orbital cannon for 1 lb kinetic impactors. You'd probably want them to be in low earth orbit so they can strike quickly. This would of course require a constellation of satellite cannon systems, probably 2000 or so would be sufficient. Also, you'd want to be standing back from your target, probably 20 feet would be safe. Probably.

Also, they'll have mixed results indoors, either putting holes through every floor above you or not quite reaching the target if you were at the base of a skyscraper. Probably not awesome for the skyscraper either...

Maybe someday everyone could have one of these for personal defense.

Omnidirectional body mounted claymore mine.

Just watch your hands.

maybe like a rapid mandatory communication field that makes talking it out feasible in all instances

Anti-tankie mines

A halberd, comparatively easy to use, long range and quite versatile.

Bag of little isopod shaped robots. They are fast moving with nuclear batteries and tungsten carbide shells and lots of sharp edges for chewing and burrowing through flesh. They can also dig into the ground a few inches and hibernate like cicadas to protect an area. Not wireless networked but instead have onboard processing for voice commands, use sense of smell for IFF and echolocation to coordinate their swarming.

Couldn't stop a gun, but they are a deterrent against using it because if you shoot me we both die but you die in a more horrible way.

A gun that shoots tiny missiles that aim at the attackers butthole and once they hit they release a jet of freezing water up their butt.

Yo-yos.

Personal forcefield with a shape of my choosing, activate either by s simple device or algorithmically based on external factors. Great for safety but also handy as an umbrella.

DMT clouds making them connect to the universe and lay down 4 minutes

If anything were possible, I have always liked AE van Vogt’s fictional weaponry:

In "The Weapon Shops of Isher", the defensive weapons sold by the shops are advanced ray guns with integrated force fields, making them highly effective against government and criminal threats. These weapons ensure citizens can defend themselves against tyranny and oppression while upholding a policy of non-aggression, aiming to foster a more just government over time.

The weapons can somehow be used to defend but not be used in an act of aggression. And the force field protects the bearer.

A fun read if you are into golden age science fiction.

https://www.prosperosisle.org/spip.php?article974#%3A%7E%3Atext=This+was+one+of+the%2Ccivilization+to+protect+them+against

We always imagine personal defense weapons as a hand held point shoot thingy.

We do? What is wrong with a baseball bat? Or a sock filled with quarters?

Laser eyes.

Now you can just look at something you want to destroy without using your arms.

Telekinesis helmets.

Now you can just think about destroying something you can't even see.

I've read somewhere and I'm not sure if it's true that there is a device that can be inserted inside the vagina which will essentially bite the rapist's penis and the only way to remove it without destroying the penis is via surgery.

High voltage contact shirt. You touch me, you fry

The best defense is avoidance. To that end, a personal time-travel / prognostication device that could both predict danger and chronoport you back to before danger was imminent would be the ultimate defense, though suppose not strictly a "weapon".

Foot held point shoot thing

Magical aura that reads intentions and zaps people. Diablo 2 paladin auras essentially.😺

personal satellite with Hatsune Miku licensed voice assistant for targeting and fire control. A few lasers of different frequency, a railgun, maybe some emergency snack pods with little chutes.

Body odour

Self defense is a fantasy of control. If you want to eliminate threats to yourself rationally, eat more vegetables, take care of your mental health, and drive carefully.

Spontaneous Human Explosion guaranteeing Mutually Assured Self-Defence/Destruction.

Like 2 Kings in a Chess game, you can't be next to each other.

Probably some kind of autonomous thingy. Like, a drone with a Taser or some shit.

This is why I have cannons loaded with grapeshot in every room of my house. Never know when I'll need to remove a thief from existence.

Temporary blinding LED flash weapon, stink bombs, vomiting, reciting the Captain Ahab monologue from Moby Dick where he's telling them to split their lungs with blood and thunder and crack their oars and backs.

Something that makes me disappear instantly and teleports me to the pub down the street. Cold beer is better than hot fight.

A tank full of sharks and gloves that dispense a sticky concentrated chum mixture with each hit. Get a couple good body blows in, knock them into the water, let nature (+/-) take its course.

A small knife? A hand-held stabby thingy.

Balls that orbit around you (think magneto of x-men)