I have done some gridfinity stuff for my desk and I will say I really like it - especially the idea of the magnets in the bins / baseplates to make really cool modular organization bins.
The baseplates let you change things around and stick things together like legos vs having to make sure random STL files are all the right size to look good together, or designing everything yourself custom for your space.
That being said, for me, the main downside is also the baseplates. I know that's what makes gridfinity gridfinity, but it just feels like a lot extra to print. Like I have to create a gridfinity space, then I can start actually organizing things. I need to add some more bins... Oh wait, first I have to print a few more baseplates. I probably need to switch to some more minimal baseplates that will print faster and use less material when I am ready to expand my setup - I printed the gridfinity refined baseplates. The features are cool (press-fit magnet slots, optional thumbscrews), but I don't think it's worth it for me given the extra time and material required.