this post was submitted on 08 Dec 2023
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[โ€“] [email protected] 9 points 11 months ago (1 children)

"Although the causal link between protein aggregates and neurodegeneration is clear, "

That's actually not clear at all.

https://www.medicalnewstoday.com/articles/alzheimers-lack-of-beta-amyloid-not-plaque-buildup-may-be-the-culprit#:~:text=However%2C%20many%20people%20accumulate%20amyloid,of%20soluble%20amyloid%20beta%20protein.

Prion may still be the cause of the misfolds, but be skeptical of the causality.

[โ€“] [email protected] 5 points 11 months ago

Yeah I have read the prion-Alzheimers hypothesis. But it's just that...a hypothesis.

Unfortunately, we still have absolutely no idea how and why Alzheimer's develops. What you've linked is a new bit of info I hadn't heard yet. Thanks for the interesting link.