Dunno. With mosquitoes, there are only a couple of species that bite humans. Eliminating those leaves plenty of other kinds of mosquitoes for birds and bats and other animals to eat. With ticks it might upset the ecosystem if it’s not the same scenario.

There was at one time a vaccine for Lyme disease, but it’s no longer manufactured. More are being worked on.

https://www.cdc.gov/lyme/about/lyme-disease-vaccine.html

https://www.masslive.com/westernmass/2026/07/westfield-health-bulletin-encouraging-news-regarding-a-lyme-vaccine.html