An 80-year-old woman with late-stage Alzheimer's took 5g of psilocybin mushrooms, slept for 19 hours, woke up and started speaking again (www.microdos.in)

submitted 2 days ago by rah@feddit.uk to c/warondrugs@feddit.uk

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A new case report published in Frontiers in Neuroscience describes an extraordinary but highly preliminary observation: an 80-year-old woman with advanced Alzheimer's disease showed temporary multidomain improvement after receiving a high dose of psilocybin-containing mushrooms.

Following administration of 5g of mushrooms, she entered a prolonged deep sleep-like state. After waking, she reportedly regained the ability to speak in full sentences, recognised family members, dressed independently, and recovered urinary continence after five years.

A later 3g dose appeared to extend some of these improvements.

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[-] StupidBrotherInLaw@lemmy.world 6 points 2 days ago

Depending on the strain, it's not too uncommon of a dose to have a proper 'trip'.

[-] Th3D3k0y@lemmy.world 3 points 2 days ago

Yeah, originally I thought it said a 5g dose of psilocybin, and I was thinking Holy Crap. But then realized it said mushrooms, did a quick search and it said 3.5g.

To be fair, I handle my drugs very badly. My local shop laughs at me because I am the only one they've ever had ask for "The weakest thing you have". So thinking at nearly 50% more than the "average" seems crazy to me.

[-] StupidBrotherInLaw@lemmy.world 3 points 1 day ago

Oh yeah, 5g of pure psilocybin would be like taking 400-600g of cubensis. Nana would have found herself perfectly functional but living in an entirely new plane of existence.

this post was submitted on 10 Jul 2026

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