I can speak to this, as I was a mod of r/AskConservatives when reddit admin sent out the communiqué that misgendering someone or othrwise denying trans identity was a reddit rule 1 ("remember the human") violation. Which I think was a step in the right direction, but those first few months were... rough. Inconsistent communication from admin, inconsistent removals by admin, and a slew of bad-faith actions from users on both the right and the left. A lot of bans given out, the head mod resigned over it, another mod was permabanned from reddit over it, and the rest of us just decided the only safe course for all our users –querants and respondents alike– was to preclude any questions touching on trans identity. (Which was unpopular with every stripe, the hallmark of a good compromise.)

Admin was already getting better at enforcing this interpretation of Rule 1 by the time I resigned my modship over the API debacle. I can only imagine they've continued to become more consistent in the time since and gradually transphobes are being weeded out with sitewide bans, or at least getting the message and keeping their bigotry to themselves. I still think it would've been better from the start to address the matter face-on, rather than shuffling it in with the proscription other dehumanizing behavior, but reddit isn't know for great decision-making or forthrightness, is it?