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New research shows weight loss is possible without GLP-1 (www.news-medical.net)
submitted 4 months ago by to c/nottheonion@lemmy.world
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[–] 36 points 4 months ago (23 children)

One day GLP-1 is going to be the catalyst for some kind of I Am Legend type shit... Mark my words.

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  • [+] 52 points 4 months ago* (last edited 4 months ago) (15 children)
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  • [–] 24 points 4 months ago (12 children)

    People will do anything for vanity. Botox is contains one of the most potent toxins known on earth, and people will happily inject it directly into their face just for the chance of a slightly smoother face.

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  • [–] 37 points 4 months ago (1 child)

    I don't want to lose weight for vanity. I want to live beyond my 50s.

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  • [–] 10 points 4 months ago* (last edited 4 months ago)

    I feel it. Living in an industrial society you really need to go against the grain to do it. As someone who has experienced substance dependency, it really is the same lizard brain urges. Avoiding hyperpalatable foods really helps. I cannot over eat oatmeal and yogurt, but bacon and hash browns absolutely. Carb portion control is really important for me, because I was eating easily over 400 calories of starches in a meal not counting anything else.

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  • [–] 13 points 4 months ago (2 children)

    I forget the exact statistic, but it's like a spoonful of botulism toxin can kill millions of people. It really is potent.

    But the difference between poison/toxin and medicine is often just dosage. There are myriad, countless medicines to discover in toxins. The toxin of an animal for instance a snake, is not one toxin, it's hundreds, each with individual action.

    There is a reason the ancient greek symbol for medicine has two snakes on it. Anyway here's an old article on it in case anyone is interested.

    https://www.nationalgeographic.com/science/article/how-harnessing-the-powers-of-venom-could-lead-to-new-medicines

    *This is not the article I originally read as that was easily ten years prior but search engines and enshitified and have decided this is the closest they will give me.

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  • [+] 11 points 4 months ago* (last edited 4 months ago) (5 children)
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  • [–] 4 points 4 months ago

    Botox is contains one of the most potent toxins known on earth, and people will happily inject it directly into their face just for the chance of a slightly smoother face

    And fentanyl can kill an entire city, but hospitals still keep it around for pain control. Diphenhydramine will make you hallucinate spiders everywhere, while you slowly die. But you can buy it over-the-counter to treat allergy symptoms. The foxglove flower can cause you to go into heart failure… But we use it to treat heart conditions.

    Dosis sola facit venenum, as the medical world likes to say. “The dose makes the poison.”

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  • [–] 4 points 4 months ago* (last edited 4 months ago) (6 children)

    Nah, it just leaves you in worse health with 2/3 of the weight gained back in less than a year after stopping. And likely keep gaining after that.

    Bug Pharma got their opioids grift shut down, so they coincidentally found out this unrelated drug was a magic weight loss pill with no downsides?

    It's way more likely they've known from the start these drugs only work while taking.

    They're not selling 2-3 years of responsible drug use, people will be on these drugs for life, because they won't stop if it means gaining weight.

    Edit:

    Actually, were at full weight regain in 2 years now....

    https://www.health.harvard.edu/medications-and-treatments/weaning-off-a-glp-1-tips-for-the-transition

    That's on top of the cardiac damage, and how your blood sugar is even more fucked up...

    People are paying all this money, fucking up their bodies...

    For something that doesn't work if you ever stop taking it

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  • [–] 4 points 4 months ago (3 children)

    Elaborate on the negative health effects please because everyone I know that's on them is having positive health effects, except some common side effects which aren't permanent (fatigue, anhedonia).

    In fact the main reason I hear people stop taking them is insurance coverage, but they'd continue if they could.

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  • [–] 4 points 4 months ago* (last edited 4 months ago) (1 child)

    everyone I know that’s on them

    I'm talking about after they stop...

    I thought that was pretty obvious.

    It works like it's supposed to while taking it, and your body adapts to it just like anything else. (Edit: well, there's chronic fatigue, vomiting, vertigo, all sorts of shit, but people on it already know about that, and you should get warned before starting. What people don't get warned about is after stopping. So that's what I'm focusing on)

    And when you stop your body doesn't have what it's used to, don't forget this is a medicine for diabetes, it will change how your body regulates blood sugar, and without it, it's not going to know what the fuck to do

    https://medicine.washu.edu/news/stopping-glp-1-drugs-can-quickly-erase-cardiovascular-benefits/

    That talks about cardiovascular issues, but again, remember that while this passed trials for diabetes treatment, there hasn't been many long term studies about what happens to people who stop taking it. And as time goes on, more people that need it less try it.

    All the studies are at ~2 years out after cessation, and those were the people who were seriously obese. The people who started later and just "chubby" are likely to see diminished gains, but the same damage. Damage that we have no reason to believe will stop accumulating after 2 years...

    That's just as far as we've studied, all this shit should have done before released to the public.

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  • [–] 2 points 4 months ago

    These drugs are bad for them? I had only heard of other benefits from them. No doubt a PR campaign, along with aggressively shutting down any negative stories/studies with the usual tactics, pioneered by big tobacco and now adopted by all the polluters and poisoners.

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