Officials will also tout the drug leucovorin as a potential autism treatment, in what President Donald Trump has billed as a “very important” announcement.

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I've got no idea what the alleged evidence for this is, but what I do know is that the people making these announcements are completely untrustworthy.

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[–] 6 points 1 year ago (33 children)

Look, acetaminophen is one of the most harmful OTC drug without this nonsese.

If they stop here, fine. But fight it like hell.

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  • [+] 15 points 1 year ago* (last edited 8 months ago) (22 children)
  • [–] 6 points 1 year ago* (last edited 1 year ago) (6 children)

    I think the reason people overdose on Tylenol, and often don't realize that's the problem until their liver is failing, is that for decades Tylenol was presented as the "safe" choice for fever and pain control. Which really just means it's not going to give little kids Reye Syndrome. But because you've absorbed that idea as a little kid, you're not looking for danger unless you specifically re-learn about overdose hazard. And too many people don't, because shitty education. Then you add all the mixed "cold and flu" OTC medications with the ingredients in tiny print, and the fact that by the time you have uncomfortable symptoms it's probably too late to pump your stomach, so people die. And that's without counting in the little ones who got into the grape chewables or drank the whole bottle of the baby's bubblegum liquid.

    Editing to add: In my experience, Tylenol just doesn't do a very good job of easing pain, which might also lead to overdose. It never worked for my severe period cramps, which Advil did. And there's a case of a man dying because he took 5 extra-strength every hour trying to control his dental pain, which I would never do but I can affirm it doesn't do shit for toothache either.

    But autism? Nah.

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  • [–] 3 points 1 year ago (3 children)

    A combination of ibuprofen and acetaminophen (paracetamol) is a crazy effective painkiller. It's been found to be even more effective than some opioids. Watch your dosage, know what you're taking, and it's perfectly safe.

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  • [–] 1 point 1 year ago

    If you do that, be sure to space them out, alternating, with at least a couple of hours between. Having done it on doctor's advice, I've noticed the Tylenol is barely enough to keep me hanging on as the previous Advil wears off and until I can take the next one. I'm not 💯% sure it was helping at all, but at least I could say to myself, "surely it will be kicking in any moment now..." until I got through to where I could start saying "Only half an hour more until you can take the good stuff."

    I think people have idiosyncratic responses to pain meds. I don't respond to Aleve either. Aspirin is mildly helpful. But a single Motrin was all I needed the day after a C-section.

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  • [–] -2 points 1 year ago (1 child)

    Huge risk of liver toxicity. Mix two drugs then drink like an average American and the liver has no chance.

    People take 2x doses of ibuprofen to recover from hangover.

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  • [–] 1 point 1 year ago*

    Then don't drink. Why would you mix poison with medicine and think that's an ok thing to do? No shit that's bad for you.

    If you are taking any kind of medicine, don't drink. If people are too stupid to realize that, then they are deserving of the Darwin Award.

    Also, don't eat grapefruit when taking medicine. That one is more forgivable because it's not obvious it's a problem.

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  • [+] 1 point 1 year ago* (last edited 8 months ago) (1 child)
  • [–] 2 points 1 year ago

    My doctors have said to take them alternating, not at the same time, and it has worked to smooth out the waves a bit although I'm definitely aware of the difference in effectiveness.

    And yes, that dude must have been crazy, badly misunderstood directions, or just in such agonizing pain he didn't care he was killing himself. Sadly, liver failure is also a painful way to go.

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  • [–] 2 points 1 year ago* (7 children)
  • [+] 3 points 1 year ago* (last edited 8 months ago) (5 children)
  • [–] -1 points 1 year ago (4 children)

    I think the point is that it can cause serious damage/death if you take too much... Which is maybe a bit unique among OTC medications specifically

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  • [–] 5 points 1 year ago (3 children)

    Yeah no. Aspirin is lethal at much lower doses.

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  • [–] -2 points 1 year ago (2 children)

    Nobody said acetaminophen is the only one like it, just that it's not common

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  • [–] 5 points 1 year ago (1 child)

    Which is maybe a bit unique among OTC medications specifically

    • spongebue
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  • [–] 1 point 1 year ago

    "a bit"

    But I suppose I was listening to something on NPR a few months ago where someone complained about describing things with varying degrees of uniqueness (eg, "a bit") because unique is technically a binary descriptor. Something I learned in that moment and apparently forgot soon after.

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  • [–] -2 points 1 year ago

    US consumers have been completely brainwashed into taking drugs for any minor inconvenience and told they are safe. The only truly safe drug is drug that does nothing.

    Because they are directly marketed to, they overdose or mix NSAIDs until their kidneys and livers fail.

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  • [+] 12 points 1 year ago* (last edited 10 months ago) (3 children)
  • [–] 4 points 1 year ago (2 children)

    Tylenol is not nephrotoxic. It's metabolized by the liver, and it can absolutely cause damage in high doses, but I think your statement is in error.

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  • [–] 6 points 1 year ago (3 children)

    Alcohol is worse. Why is no on banning it?

    If you take too much of something, it becomes harmful. What an epiphany.

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  • [–] 1 point 1 year ago* (last edited 1 year ago) (2 children)

    I mean the sheer amount of sugar in our food has to be the largest cost to lifespans/healthcare in the U.S.

    Id like to see us make a change over time introducing not bans but better ways to regulate packaging.

    I don't want it to have warnings everywhere and dead fetuses and shit, I just want things like, green boxes, blue boxes, magenta boxes, stuff like that. Maybe an easy to see letter in the lower left for those who are color blind

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  • [–] 1 point 1 year ago (1 child)

    What dead foetuses? Paracetamol doesn't do that.

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  • I was talking about boxes/cans for food, like say ramen, cheese it's, swiss cake rolls, green beans what have you.

    The dead fetuses is a reference to the way countries have tried to use scare tactics on products to get them not to use a product. Like cigarettes. I don't want them to do that shit with food as well, but bad diets, such as added high fructose corn syrups and what not I was advocating for foods having main colors for boxes and maybe a letter on the can for colorblind people. That says to a purchaser who isn't going to read, this soup isn't as bad for me as this other soup. Or when buying snacks for their kids they know are going to sneak them, they can buy snacks/chips etc that are better or worse intentionally with little effort. Bad diets have been and will always be the #1 highest cost to a countries healthcare and leading the natural early death rates.

    Example of what I don't want:

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  • It's also worth noting that it's pretty much the only OTC painkiller you're allowed to take while pregnant, so

    A. I would imagine the percentage of people who've taken it at least once while pregnant is staggeringly high, to such a point that this would be very difficult to adequately establish causation and

    B. They are, once again, just screwing over pregnant people

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