That's the history of memes.

So at first, people were making fun of a bad artist with a bad comic. In that context it wasn't edgelord material, he was an adult and he can handle being the butt of a joke.

Then, the meme gained a life of its own (its context was itself) and that old context ceased to matter. It wasn't about the artist anymore, but without context it still wasn't edgelord material.

At no point was the joke edgy because the joke was never about miscarriage.