My girlfriend's cat got very sick one day and we had to feed her through a tube.

Well one day she got better and decided that she wasn't going to put up with tube feeding. I am a 6ft, 230lb man and I shit you not, I had to put my entire body weight on her to keep her from squirming. Every ounce of my strength went into holding her down so that the tube wouldn't rip out of her throat as the food was going down. I couldn't believe how strong a kitty could be when you try to get them do do something they don't want to do.

So no I don't think I could take a house cat in a fight.