31
submitted 2 years ago by [email protected] to c/[email protected]
you are viewing a single comment's thread
view the rest of the comments
[-] [email protected] 3 points 2 years ago

IMO the title is incorrect because the common interpretation of getting "burned out" is that of the same individuals of a population losing effectiveness after working hard. The article even likens the term "exhausted" the same interpretation of the phrase:

Altogether, our research suggests that T cells in tumors are not necessarily working hard and getting exhausted. Rather, they are blocked right from the start.

This same quote describes the truth of the phenomenon where it's not individuals getting "exhausted", but cellular signalling permanently altering the expression of T cells to make them less and less effective.

A more correct title would be something like:

Cancer makes every generation of T cells worse than the last

[-] [email protected] 1 points 2 years ago

Ahh, That makes sense.

this post was submitted on 06 Aug 2023
31 points (100.0% liked)

Science

14077 readers
1 users here now

Studies, research findings, and interesting tidbits from the ever-expanding scientific world.

Subcommunities on Beehaw:


Be sure to also check out these other Fediverse science communities:


This community's icon was made by Aaron Schneider, under the CC-BY-NC-SA 4.0 license.

founded 3 years ago
MODERATORS