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cross-posted from: https://news.abolish.capital/post/60188

Since 2020, it has been well-documented that many people suffer new chronic symptoms following a Covid infection, including cognitive impairment, shortness of breath, fatigue, loss of smell, joint pain, vertigo, chronic tachycardia, tinnitus and more—similar to what was reported during the first SARS pandemic. In July 2021, the US government gave the condition known as “post-acute sequelae of Covid-19” (PASC) an ICD-10 (International Classification of Disease) code, identifying it as an official disease, as well as recognition as a disability. Patients popularized the term “Long Covid” to describe the condition.

There are still unanswered questions about how Long Covid functions and how its various subtypes relate. But the evidence of disease burden keeps piling on. In the last year alone, new studies have indicated that: 1) the prevalence of Long Covid may be much higher than assumed; 2) Long Covid is costing the world’s economy billions; and 3) some autoimmune symptoms of Long Covid can be transferred from humans into mice via autoantibodies.

You won’t find many articles about these studies and breakthroughs in national corporate media. Instead, you will find lengthy articles arguing that Long Covid is a psychological condition—that mass psychogenesis is a better explanation for millions of newly chronically sick people (and animals) than the Covid virus.

‘The truth’ is out there

NYT: The Truth About Long Covid Is Complicated. Better Treatment Isn’t.

Adam Gaffney and Zackary Berger (New York Times, 8/18/21) argued that the illness might be caused by “the sharp increase in psychological distress amid the tragedy of the pandemic.”

The psychologizing of Long Covid has been a recurrent theme in the national media since 2020, especially in outlets that cultivate a high-minded audience. The idea has appeared in the New York Times (8/18/21), New Yorker (10/20/21), New Republic (12/8/22), Slate (3/19/23, 3/26/23), Time (11/15/23) and Wired (6/1/26), among others. Media outlets that trumpet their journalistic integrity and commitment to facts have used their prestige to launder an unproven, anti-science conspiracy theory, often with headlines that refer to “the truth” about Long Covid.

The Atlantic (e.g. 9/12/22, 9/26/22) has been a notable exception, where journalist Ed Yong did award-winning Long Covid coverage from a scientific and patient-centered perspective. Mother Jones (e.g., 8/6/24, 7/19/24) also has disability coverage that consistently frames Long Covid as a medical crisis.

Perhaps surprisingly, the conservative New York Post (e.g., 2/16/24, 7/27/25, 2/1/26, 2/10/26) reports frequently on advances in Long Covid research, covering stories ignored by the centrist and liberal outlets listed above, although the Post (2/15/24, 12/4/25) has also published contrary opinion pieces.

Most of the skeptical coverage on Long Covid draws on the history of the psychologization of chronic diseases that Covid commonly causes, especially Myalgic Encephalomyelitis, also known as Chronic Fatigue Syndrome (ME/CFS). The disease causes energy and exercise limitations, sometimes severe. Studies estimate about 50% of people with Long Covid meet the criteria for ME/CFS.

Despite more than 30 years of research confirming the biological mechanisms involved in ME/CFS—which are acknowledged by the CDC—experts are often drowned out in the media by a cadre of psychiatrists and others determined to frame it as a mental health issue.

To varying degrees, articles that psychologize Long Covid tend to acknowledge that the physical symptoms experienced by patients are real, just unlikely to be caused by the Covid virus or any other biological origin. They often point to a vague mind-body paradigm as an explanation, but one in which the mind controls the body far more than the reverse. Overall, these articles emphasize that patients would benefit more from mental health and/or social service solutions than research and medicine.

The ‘brain retraining’ solution

Wired: The Painful Truth About Long Covid

Wired*‘s piece (6/1/26) faced criticism for cherry-picking data and patient accounts. As Virology Blog (6/9/26) noted, “Levinovitz is straining mightily to interpret patients’ experiences in ways that conform to a preferred narrative.”*

A recent piece in Wired (6/1/26), titled “The Painful Truth About Long Covid,” advocated for a model known as “brain retraining” to treat Long Covid. This approach focuses on rewiring the brain to not overreact to perceived threats, based on the belief that the overreaction, not the exposure, is the primary driver of symptoms. The article cited some patients who say they benefited from the approach.

The author, Alan Levinovitz, previously disclosed his views more bluntly on X last year, posting, “I happen to believe 60–80% of Long Covid is…psychogenic symptoms/illness.”

In Wired, Levinovitz took aim at claims that Long Covid patients with ME/CFS are limited in their ability to exercise. He argued that the problem isn’t exercise, but the belief that exercise is harmful. “Patients cursed themselves by believing their symptoms had a strictly biological cause,” he wrote.

Levinovitz cited an influential British study from 2011, known as the PACE trial, which determined that Cognitive-Behavioral Therapy and guided exercise were appropriate treatments for ME/CFS. While he acknowledged that the PACE trial faced backlash and fell out of favor, he failed to mention that scientists determined the study was invalid due to improper methodologies. Levinovitz portrayed patient advocates as misguided fanatics who have interfered with progress by pushing back on PACE and exercise/mind-body approaches.

The Wired article has faced mass outrage and criticism from patients, scientists, doctors and journalists. Articles and social media threads have debunked its claims on scientific grounds, citing its omission of key studies, including mind-body studies that did not support the model’s effectiveness. People mentioned in the article have spoken out against how they were represented. Some critics have shared their own experiences with brain retraining, describing it as a cult-like multi-level marketing scheme.

After publication, Levinovitz spent days fighting with critics online, dismissing research findings and issuing personal attacks, even going after one woman’s efforts to crowdfund for her medical care. (He has since deleted some posts, and acknowledged that he misstated facts in one thread.)

A petition is circulating, calling for the article’s retraction, signed by more than 1,700 people. Wired’s only response has been to issue an “update,” acknowledging two corrections. One was significant: The author mistakenly referred to Myalgic Encephalomyelitis as “Myalgic Encephelitis.” The outlet has not responded to questions from FAIR about the article, including about whether it was factchecked.

The ‘functional’ theory

New Republic: We Might Have Long Covid All Wrong

“A chronic illness that appeared to be triggered by viral infection could just as easily have been triggered by the trauma of the pandemic itself,” Natalie Shure asserted in the New Republic (12/8/22).

Long Covid advocates similarly campaigned against a 2022 article in the New Republic (12/8/22) by journalist Natalie Shure, which argued that the disease might be a functional neurological disorder (FND), a popular belief among the skeptical crowd. Formerly known as conversion disorder, FNDs are thought to be psychological in origin. They are often used as a catch-all for diseases without clear explanation—a modern-day “hysteria” diagnosis. Like Levinovitz, Shure doubted that exercise can be seriously harmful for people with ME/CFS.

A letter published in the Public Herald (1/25/23), signed by over 200 medical doctors, researchers and patients (including myself), gave a point-by-point rebuttal to Shure’s article. The New Republic issued only a small correction, but never again published Shure, who had been a consistent contributor until then.

Shure, as it happens, is married to Dr. Adam Gaffney, an early and vocal skeptic of Long Covid. In a February 2021 blog post, he wrote that we should “question the causal link between the virus and some ‘Long Covid’ symptoms.” He also argued that Long Covid was showing up mostly in wealthy white people. In fact, studies show that Black and Hispanic people have higher rates of the disease than whites.

In August 2021, the New York Times (8/18/21) published an op-ed by Gaffney and Dr. Zackary Berger with a “truth about Long Covid” headline. It argued that funding should not be wasted on researching Long Covid, but that patients could benefit from counseling and social services. Since Gaffney’s op-ed, research has uncovered mitochondrial dysfunction, vascular issues and reactivation of Epstein-Barr in Long Covid patients.

Time: How to End the Futile Blame Game Over Failed Long COVID Research

“Research directed at finding diagnostic and mechanistic clues to Long Covid” is a waste of time, Steven Phillips and Michelle Williams wrote in Time (11/15/23), because there may be “nothing to find.”

A Time magazine article (11/15/23) echoed Gaffney’s concerns about research funding. “But what if the medical research community spends years and hundreds more millions of dollars digging a dry hole?” the article  by Steven Phillips and Michelle Williams asked.

This rhetoric has a familiar antecedent: “What if someone showed you that billions of tax dollars may have been spent chasing the wrong cause of AIDS?” Nightline (4/4/94) asked in a 1994 segment titled “Is HIV the Causative AIDS Agent?” The idea that AIDS had a different cause than HIV was popular during the first six or so years of the pandemic, before the discovery of HIV medications. Still, the theory appeared in Harper’s Magazine (3/06) as late as 2006, and on Joe Rogan’s podcast multiple times (11/7/12, 2/13/24).

During the 1980s, AIDS deniers promoted homophobic ideas that the disease was caused by lifestyle choices or spiritual malaise. With Long Covid, skeptics promote lifestyle judgments around exercise and mental health. Patients who are bedbound are accused of “deconditioning” and/or an irrational fear of exercise.

Since 2020, numerous professional athletes, who probably do not fear exercise, have described a sudden onset of incapacity following infection, not from weeks or months spent deconditioning in bed.

The biomarker issue

NIH: A New Clue Behind Long Covid Symptoms

One recent study (Cell, 5/28/26; NIH, 6/17/26) found that healthy mice developed Long Covid symptoms when injected with autoantibodies from patients.

“There is no ‘Long Covid,’” Levinovitz posted on X, just after publishing his article advocating for brain retraining to treat it. “Nothing about Long Covid adds up,” his Wired story (6/1/26) started, citing conflicting information about prevalence.

These articles exploit the fact that Long Covid is a misunderstood and heterogenous illness to make it seem unintelligible and impossible. But Long Covid/PASC has always been defined as an umbrella diagnosis. Per the ICD-10, PASC includes anyone who has suffered chronic symptoms post-infection for three or more months. That can include gastroparesis, kidney disease, cognitive impairment or an immune system disorder. The Long Covid skeptics are rarely clear about which symptoms and conditions they believe would respond to therapy, exercise and mind-body awareness.

Most Long Covid skeptics treat the fact that the disease doesn’t have a single “biomarker” as an easy way to invalidate it. As Levinovitz wrote, “Part of the definitional problem for long Covid is the absence of definitive biomarkers: genes, antibodies, any unique physiological signature of the illness.”

Evidence of absence is not absence of evidence. Long Covid research is still advancing, with limited funding relative to its impact. A unique biomarker, like indication of persistent viral activation, might one day be discovered in people with chronic symptoms.

Biomarkers are not necessary to define a disease. Some diseases, like Sjogren syndrome and migraines, are diagnosed clinically, based on symptoms. Many diseases, including multiple sclerosis, Alzheimer’s disease and lupus, were diagnosed clinically until biomarkers were discovered, and even those markers aren’t always considered absolute indicators.

Long Covid may not have a single biomarker yet, but patients often do have biomarkers, like abnormal lymphocytes, irregular tachycardia and/or [reactivated infections](https://www.thelancet.com/journals/langlo/article/PIIS2214-109X(2400010-X/fulltext). Providers willing to order those tests often don’t take insurance and can be hard to locate.

Both Shure and Gaffney further question if it’s possible to even identify a Long Covid patient.  To them, the fact that many alleged patients didn’t have antibodies showing after a Covid infection was a slam-dunk reason to doubt Long Covid. But studies show that a significant percentage of infected people do not seroconvert—create antibodies—and those patients are more likely to develop Long Covid.

Investigative journalism or opinion?

Slate: Long COVID Comes Into the Light

Slate‘s Jeff Wise (3/19/23) hopes to put Long Covid in the rearview mirror so we can join Joe Biden in declaring that “Covid no longer controls our lives.”

Most of the articles psychologizing Long Covid look like long-form investigative journalism. They include data and quotes from purported experts, often the same group of contrarians. Yet few of these articles were written by health journalists. Shure is an exception, a journalist who writes often about health issues, though usually from a sociopolitical perspective.

Levinovitz is a professor of religion who has written one article on Long Covid in the past, as well as a book arguing that people’s food sensitivities are often psychological. In Wired (6/1/26), he refers to the arguments around Long Covid as a “religious war.”

In 2023, Slate (3/19/23) published a much-criticized article that attempted to discount Long Covid altogether. It was written by Jeff Wise, who reports mostly on aviation and psychology. He is best known for his work on the missing flight MH370, although he received criticism, including from aviation experts, for pushing conspiracy theories in a documentary on that subject.

Wise published a book in 2009 titled Extreme Fear: The Science of Your Mind in Danger, which might explain his interest in Long Covid. He has argued online that ME/CFS patients face a fear of exercise. Some of these writers seem to be applying their specialized thought experiments to Long Covid.

Slate (3/26/23) published a second article in 2023, headlined “Is Long Covid Linked to Mental Illness?” that cited Gaffney and argued for a possible psychosomatic understanding of the disease. The writer, Grace Huckins, is a neuroscience PhD student interested in mind-body connections.

“As of yet, there is no conclusive proof that stress or mental illness can contribute to Long Covid,” she wrote. She then posed a bunch of hypotheticals, including:

If psychological factors have a considerable role to play in generating and maintaining Long Covid, then psychological treatments should be studied just as rigorously as drugs like Paxlovid.

Huckins did not acknowledge that psychiatric medications like low-dose Abilify are often given off-label to treat Long Covid, but not for their psychological properties.

Most of these writers previously disclosed their skeptical views on Long Covid before publishing long-form stories on the illness. Why are news outlets outsourcing articles about one of the most important health stories of the decade to ax-grinders? If the media wanted to inform the public about Long Covid, there are many qualified writers who share information and findings, in journals like Nature and outlets like the Sick Times.

National corporate media have created a controversy—”is Long Covid a real medical disease?”—which never existed in any serious form among the experts who research Covid, instead of investigating the actual nuanced debates in that field, like whether viral persistence drives symptoms. These media have given credibility to writers eager to entertain the supposed controversy, while marginalizing writers who start from the premise, widely shared among actual researchers, that Long Covid is a medical disease.

There is a similar trend in the media when it comes to trans issues, as FAIR (12/1/25) previously reported. The media consider sources to be “neutral” when they aren’t “deeply involved in the issue,” which excludes both medical experts and people actually receiving gender-affirming care.

Old media habits

FAIR: Media Baffled by Wheelchair ‘Miracles’ Because They Don’t Understand Disability

Justine Barron (FAIR.org, 1/12/26): “Media amplify the biased hot takes of random individuals on social media who push the age-old narrative that disability is dubious.”

Long Covid is not the only disease or disability to be treated skeptically and/or psychologized in the media. Media treatment of chronic disease and disability is a consequence of newsrooms with poor disability representation.

As I wrote about for FAIR (1/12/26), media have a habit of assuming that claims of disability and disease are overstated, including when students say they need accommodation. A New York Times series (11/9/21) posited that pain is largely driven by the mind, not broken bones or pinched nerves, so it could be treated with psychotherapy.

Stories psychologizing Long Covid also support a media agenda to minimize the Covid pandemic generally (FAIR.org, 1/10/23). The Biden administration declared the pandemic over after the introduction of vaccines, and stopped collecting consistent data on transmission and death. Outlets like NPR followed suit, regularly referring to the current era as “post-Covid.” Yet Covid wastewater levels show that the virus has continued surging in the years since, sometimes to levels higher than in 2020.

By neglecting to report seriously on Long Covid, corporate media often miss a huge part of the stories they tell. For instance, some media outlets (e.g., ABC News, 2/3/25) did report on a 2025 CDC study that more than 1 million children in the US have Long Covid, which was data from 2023. A more recent study indicates that Long Covid is now the No. 1 chronic illness in children in the US, surpassing asthma.

Yet Long Covid isn’t mentioned in media reports on the crisis in chronic student absenteeism (e.g., New York Times, 2/2/24; Washington Post, 5/7/22; New Yorker, 1/15/24), or the crisis in childhood test scores and cognition (e.g., AP, 6/10/26; New Yorker, 6/12/26). Instead, the media tend to scratch their collective head and blame anxiety, screens and lockdowns.

The media tendency to ignore, deny and/or psychologize Long Covid causes significant harm to both patients and the general public, who are not being warned of the risk. Patients face disbelief and bigotry from families, workplaces and even doctors, who often get more information from the media than from journals. The gulf between medical research and practice is estimated to be 17 years on average.

Prejudices against patients are reinforced when a news outlet’s most in-depth, academic-sounding articles on Long Covid attempt to undermine the reality of the disease.


From FAIR via This RSS Feed.

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I don't have anything to do with it, but figured some folks might be interested.💁 rainbow-has

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The worst people on earth don't want you to get vaccinated.

Despite all Americans having been either infected with and/or vaccinated against COVID at this point, writes Califf in the commentary, the studies’ findings demonstrate that “updated booster vaccines provide continued protection against major adverse clinical outcomes, including lower risks of major cardiovascular events, hospitalizations, and all-cause death.”

And even though the magnitude of the protection is modest and wanes over time, argues Califf, the cardiovascular benefits of vaccination outweigh the potential risks. What’s more, he adds, studies continue to suggest major risks tied to COVID infection, including neurodevelopmental disorders in children born to those with serious COVID infections.

Post-COVID condition, also known as long COVID, is another important consideration. “Ongoing studies point out the substantial effects of post–COVID-19 condition. Millions of individuals in the US, including a substantial number of children, experience loss of function and diminished quality of life due to the disease’s sequelae,” Califf writes. “Many observational studies have found an association between previous vaccination and a reduced risk of post–COVID-19 condition

This also means covid is still fucking people up to a significant degree.

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submitted 1 week ago by Clippy@hexbear.net to c/covid@hexbear.net

doubt if most people care, but around 9:40 on Rick and Morty Season 9 Episode 5 Jer Bud, long covid was mentioned by the character space beth

the character asking outloud if she has long covid.

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The Causes of Long Covid (www.science.org)
submitted 3 weeks ago by git@hexbear.net to c/covid@hexbear.net
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submitted 1 month ago by Keld@hexbear.net to c/covid@hexbear.net

A pretty decent critique of a study thats been making the rounds.

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I wish they were closer to me, but it's nice to see. catgirl-heart

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cross-posted from: https://news.abolish.capital/post/50077

There have now been 11 confirmed cases of hantavirus connected to an outbreak from the luxury cruise ship MV Hondius, which departed Argentina on April 1. Although transmission is difficult, three people have died, and with a mortality up to 40 percent, global spread would be devastating. It’s also no surprise that people are concerned — particularly since we are just six years out from the peak of the Covid-19 pandemic, which showed us exactly how capitalism and the ruling class respond to pandemics.

The Hantavirus(es) and the Cruise

The hantaviruses are part of a group of viruses found primarily in rodents. And while humans typically acquire them in contact with rodent feces, the Andes strain can spread from human to human, though experts have claimed transmission in this way is very difficult. The virus has a six- to seven-week incubation period, which makes the virus harder to track and allows people to go long periods of time without exhibiting symptoms. All of this, plus the virus’s very high mortality rate, makes human to human transmission all the more concerning.

So if more people have been exposed, where are they now? The almost 150 passengers and crew members have mostly returned to their home countries around the world for ongoing intensive monitoring and treatment. The WHO has left it up to each country to determine necessary precautions which vary widely from strict quarantine in healthcare settings (Spain) to home quarantine (the Netherlands).

In the United States, 18 of the passengers are being treated at the Administration for Strategic Preparedness and Response Regional Emerging Special Pathogen Treatment Center at the University of Nebraska Medical Center/Nebraska Medicine (UNMC) in Omaha. Another two passengers were taken to Emory University’s Serious Communicable Diseases unit in Atlanta. Peculiarly, and somewhat troublingly, while patients at UNMC are supposed to be monitored for 42 days, Dr. Brendan Jackson, the CDC’s acting director of high-consequence pathogens and pathology, recently said patients may be able to go home during the monitoring period, but only if they have support to isolate at home.

Most recently, U.S. officials said they were monitoring additional people across the country who were passengers on an April 25 flight from Johannesburg and exposed to someone known to have been infected, bringing the new total of those being monitored in the U.S. to 41.

The Spectre of Covid-19

As the hantavirus situation plays out, officials around the world, including in the U.S. Department of Health and Human Services, have repeatedly tried to reassure the public, downplaying the risk of large-scale spread. But there is plenty to still be concerned about. As the New York Times reports:

And this is just specifically related to disease response. Whether it is approving forever chemicals in pesticides, scraping the endangerment finding, or deciding that it will no longer evaluate the health impact and lives saved when regulating air pollution from new power plants, the Trump administration is not showing signs that it’s concerned about public health overall. But it’s not just the Trump administration — both parties are more than willing to sacrifice lives at the altars of imperialism (cough, Genocide Joe, cough) and capitalism.

As a physician who worked in hospitals throughout the Covid-19 pandemic, I’m inherently skeptical despite expert reassurances. Working in healthcare has provided me example after example reinforcing how little the ruling class cares about the health of the general population. And the pandemic showed us clearly that capitalism does not care about people unless they are generating profit.

During Covid’s peak, we saw how the bourgeoisie around the world were more than willing to reopen economies and force people back to work in order to keep the profit flowing. Hell, what do they care about any of us, to be honest? They know they can run to their luxury condos — or even their disaster bunkers — as we all are put at risk. It’s in this context that what to believe and not to believe around the response to the Andes virus is inevitably going to be blurred by how the bourgeoisie managed Covid-19.

Whether it’s downplaying the transmissibility of the disease, distorting the scientific data, or focusing on magic bullet solutions, capitalist states are making many of the same mistakes they made in 2020. Capitalism inevitably breeds crises, yet also tries to come up with profitable, commensurable “solutions” to the crises it generates all while avoiding any regulation that could slow profit accumulation.

Under this system, there’s an aura of “don’t worry about it, we can innovate our way to a solution.” Rising greenhouse gases driving us toward climate collapse? Don’t worry, we can just suck up pollution — or better yet, “blot out” the sun. During Covid’s peak, instead of making sure safety measures were in place and paying people to stay safe at home, the focus was put on rolling out vaccines as the magic bullet to reopen economies. All this while the virus continued to spread, leading to excess death and countless cases of long Covid. God forbid people be able to shelter in place or keep themselves safe as a deadly virus is on the loose. This would be too threatening to the system’s maximization of the extraction of surplus value.

Today, similar discussions are being thrown around with the hantavirus. From NBC to Forbes, the discussion is already leaning toward how a vaccine is in the works, and the risk of hantavirus is continually downplayed.

Hantavirus or Not, Capitalism Will Breed Pandemics

Whether this virus becomes the next devastating pandemic or not isn’t the real question. The real question is: what happens when — not if — the next one hits?

Under a global economic system that constantly places profit above public well-being, it’s only a matter of time before the next pandemic arrives. Covid-19 showed us this and the current reality only further confirms it. Whether it’s gutting public health programs, destroying the environment, funding genocides, or cutting CDC staffing while withdrawing from the WHO, the message is clear: health and well-being are secondary.

Hopefully the hantavirus outbreak does not continue to spread and it actually just serves as a warning shot. Regardless, as the ruling class continues to destroy ecosystems, push wildlife into closer contact with humans, and defund the very institutions meant to protect us, they are actively manufacturing the conditions for the next global health catastrophe.

And when that catastrophe comes, we can’t expect capitalism to save us. We’ll get the same playbook: reassuring lies, profit-driven “solutions,” and a ruling class that runs and hides in luxury enclaves while the rest of us are sacrificed at the altar of capital.

We cannot innovate our way out of this cycle. In the search for magic bullets to each pandemic, the reality remains: no magic bullet will fix a system that breeds pandemics for profit. We need a system that prioritizes human need over capital accumulation — a system of free, accessible healthcare for all, controlled by workers and patients rather than insurance companies and pharmaceutical executives. A system where the working class controls both healthcare and research institutions, along with media companies that disseminate public health information.

At the same time, we need massive investment in public health infrastructure, not austerity and cuts. We need an internationalist, coordinated response to disease, not one driven by profit and national interests. We need an end to the environmental destruction that fuels zoonotic disease emergence, and an end to the wars and poverty that create the conditions where pathogens thrive.

And we will have to fight for it — in our workplaces, in our unions, and in our communities, building the world we need, because the ruling class will never build it for us. The next pandemic is coming. The only question is whether we will be ready.

The post Hantavirus, Capitalism, and the Spectre of Covid-19 appeared first on Left Voice.


From Left Voice via This RSS Feed.

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hopium

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submitted 1 month ago* (last edited 1 month ago) by rootsbreadandmakka@hexbear.net to c/covid@hexbear.net

Feels like covid in late 2019/early 2020. I’m half expecting to read some Reddit post from some guy in a major city saying that he has some weird cold and his doctor told him not to go outside but he’s unable to test so he’s unsure what it is. Of course I said the same thing about bird flu last year and that has yet to pop off. The difference of course being that hantavirus has confirmed human-to-human transmission, bird flu never did.

Thoughts? Are you preparing for covid 2? Think it’ll fizzle out?

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Early human embryonic cells may be vulnerable to SARS-CoV-2 infection

SARS-CoV-2

Credit: Unsplash/CC0 Public Domain

A University of California, Riverside study reports that cells in the earliest stages of human development could be susceptible to infection by SARS-CoV-2, which causes COVID-19, offering new insight into how the virus interacts with developing human tissues and why that may matter for pregnancy research.

Using a "disease-in-a-dish" laboratory model of early human embryonic development, researchers Ann Song and Prue Talbot examined how different cell types respond to exposure to artificial SARS-CoV-2–like particles. They found that multiple early embryonic cell types can be infected, but susceptibility varies significantly. Cells destined to become the ectoderm — the layer that eventually forms the skin and nervous system — were by far the most vulnerable.

"Ectodermal cells were about 23 times more susceptible to infection than undifferentiated embryonic stem cells and six times more susceptible than mesodermal cells," said Song, a doctoral student in the Department of Molecular, Cell and Systems Biology and the first author of the study published in Frontiers in Cell and Developmental Biology. Mesodermal cells are the middle layer of embryonic stem cells that differentiate into essential tissues.

The heightened vulnerability appears to be driven by several biological features. The researchers found ectoderm cells show elevated activity of TMPRSS2, a protein that helps the virus enter cells. In addition, these cells have a thinner glycocalyx, a protective sugar coating, making it easier for the virus to bind to the ACE2 receptor — a membrane-bound protein that acts as the primary entry point for the SARS-CoV-2 virus — on the cell surface.

"Together, these factors create conditions that strongly favor viral attachment and entry and highlight how certain early cell types may be particularly permissive to infection," said Talbot, a professor of the graduate division and Song's advisor.

"Our findings highlight urgent need for clinical studies to monitor the long-term neurological and developmental health of infants born to mothers who were infected with COVID-19 during early pregnancy," she said.

The study was conducted using experimental models rather than in pregnant individuals. The findings do not demonstrate that embryos are infected during real pregnancies, but they do show that, in principle, very early developmental stages could be biologically susceptible to the virus.

The results provide insight into the first weeks of human development (weeks 1–4), a period that is difficult to study directly. Because the ectoderm gives rise to the brain and nervous system, its high susceptibility raises important questions about potential developmental risks. If infection were to occur during this stage, it could contribute to neurodevelopmental delays or structural abnormalities.

"This study gives us a clearer picture of how SARS-CoV-2 can interact with human cells at the earliest stages of life," Talbot said. "Further research will be needed to understand the real-world implications."

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Several next generation Covid vaccines are now advancing into mid- or late-stage trials. So this month, I have started a new section—a watchlist of featured vaccines that are both at more advanced stages of development, and reporting ongoing recent progress. I highlight 3 vaccines in particular—from Japan, South Korea, and the US—with a further 6 included in the watchlist. I hope this focus on advancing vaccines will make the progress in next generation vaccines clearer. The post begins there.

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submitted 3 months ago by JoeByeThen@hexbear.net to c/covid@hexbear.net
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#Doctors share why it’s still important to take the virus seriously.

#Key Points

  • COVID still causes significant hospitalizations and deaths despite declining severe impact rates.
  • Re-infections increase risk for certain health issues.
  • Annual vaccination is key to preventing severe disease and reducing long COVID risk.

According to data from the Centers for Disease Control and Prevention, COVID was associated with an estimated 290,000 to 450,000 hospitalizations and between 34,000 and 53,000 deaths between July 2024 and July 2025, the most recent year that data is available. These stats show just how much the virus is still impacting us.

For comparison, here's how the flu impacted people in 2024-2025 Which was a more severe flu season than normal:

CDC estimates there were 51 million influenza (flu)-related illnesses, 23 million medical visits, 710,000 hospitalizations and 45,000 deaths during the 2024-2025 flu season. Based on CDC criteria, the severity of the 2024-2025 season was high.

The estimated flu-related illnesses and medical visits are higher than the 2017-2018 season, the last high severity flu season. Estimated hospitalizations are the same as 2017-2018, while estimated deaths are lower.

I guess this is the new normal. Double the amount of severe respiratory disease than before, and little to no seasonality.

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Lauren Olamina Is Not The Leader You Want (walkingunwound.substack.com)
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submitted 3 months ago by Clippy@hexbear.net to c/covid@hexbear.net
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submitted 3 months ago by dat_math@hexbear.net to c/covid@hexbear.net
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submitted 3 months ago by Clippy@hexbear.net to c/covid@hexbear.net
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Mask Math site (thelemmy.club)
submitted 3 months ago by culpritus@hexbear.net to c/covid@hexbear.net

https://aatishb.com/maskmath/

Found this interactive "Mask Math" site with info on how effective masking can be under different circumstances.

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submitted 4 months ago by JoeByeThen@hexbear.net to c/covid@hexbear.net

From in the Comments:

  • Applegate has a chronic autoimmune condition (MS)
  • Kimmel has narcolepsy which is also autoimmune in mechanism
  • Kimmel has a daughter with tetralogy of Fallot, a congenital heart defect

Just spinning that roulette wheel and making funnies. doomer

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submitted 4 months ago* (last edited 4 months ago) by QuietCupcake@hexbear.net to c/covid@hexbear.net

Thanks to ☆ Yσɠƚԋσʂ ☆ @yogthos@lemmy.ml for this one, I saw posted here. Wasn't expecting to see a comic so perfectly nail it.

Edit: Aaaand now I see that this was basically posted yesterday, but as a link to the xcancel thread about it. So I guess here's the direct link to the comic at least.

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submitted 4 months ago by mononoke@lemmy.sdf.org to c/covid@hexbear.net

I don't know how to share the images themselves, I think SDF Lemmy's image hosting is still broken, but it's very cute and well-cited.

"Wearing a mask is the easiest way to make a direct, positive impact on your community"

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