the most oppressed minority

I like Jane sterling from the jimquisition channel, she is a trans gamer that strongly advocates against greedy gaming companies, lgbt rights and is and wrestler as a side gig

Lextorias uses hey/they pronouns and iirc identifies as bisexual. He makes video essays mostly on games and anime.

You can also search the LGBTQIA+ tag on your favorite games on twitch.

JustinGaymes on twitch is a smaller, but super wholesome and chill creator. Usually he plays sims and overwatch, as well as other random stuff.

If you're into streaming, Kris Yim is they/them and openly gay. They stream using a VTuber model they began using as a joke, but they're very grounded and aren't corporate or bizarre like other VTubers usually are. I can decently recommend them. https://youtube.fandom.com/wiki/Kris_Yim

They're also a professional animator, so they'll sometimes do drawing streams to break up their gaming ones if that interests you.

Ian on the youtube channel Brutalmoose used to do a lot of gaming content, though his content has evolved beyond that nowadays. It's very hard to explain his content, sort of "avant-garde reviews of various things." Though he still streams games on his second channel from time to time if that's the only thing you're looking for.