this post was submitted on 07 Dec 2023
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Science

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[–] [email protected] 16 points 11 months ago (1 children)

It is truly amazing to think that the newest generation of people might live in the age where the richest people in the world never die naturally.

[–] [email protected] 8 points 11 months ago (1 children)

And here am I thinking that I might be living in an age when I can be forced to become young again so that I can't retire.

[–] [email protected] 4 points 11 months ago* (last edited 11 months ago) (1 children)

No. Why pay money to make the workforce young and immortal, when they can just replace you with cheaper and more easily manipulated workers in 20-30 years?

[–] [email protected] 2 points 11 months ago* (last edited 11 months ago)

Because they're seeing how that "replace you with cheaper and more easily manipulated worked in 20-30 years" is working now. They might try relying on breeding, but when that falls short (like when all the boomers suddenly start retiring), they'll realize they can't trust us to produce our replacements.

If they keep the workforce young and immortal, they can have unlimited workers. No one can demand more money because they can replace you with one of the hundreds of drones waiting in the wings. So we'll all be kept young and desperate.

Edit: gesture typo.

[–] [email protected] 5 points 11 months ago (1 children)

This is the best summary I could come up with:


That reversibility makes a strong case for the fact that the main drivers of aging aren’t mutations to the DNA, but miscues in the epigenetic instructions that somehow go awry.

Once “aged” in this way, within a matter of weeks Sinclair saw that the mice began to show signs of older age—including grey fur, lower body weight despite unaltered diet, reduced activity, and increased frailty.

The researchers are attaching a biological switch that would allow them to turn the clock on and off by tying the activation of the reprogramming genes to an antibiotic, doxycycline.

Sinclair is currently lab-testing the system with human neurons, skin, and fibroblast cells, which contribute to connective tissue.

That could mean that a host of diseases—including chronic conditions such as heart disease and even neurodegenerative disorders like Alzheimer’s—could be treated in large part by reversing the aging process that leads to them.

Sinclair has rejuvenated the eye nerves multiple times, which raises the more existential question for bioethicists and society of considering what it would mean to continually rewind the clock on aging.


The original article contains 1,267 words, the summary contains 178 words. Saved 86%. I'm a bot and I'm open source!

[–] [email protected] 1 points 11 months ago (2 children)

What a bullshit title.

Its not because A makes you older (or here, makes mice look older) that you are solving aging by removing A.

Eating, in the long run,makes us older.

[–] [email protected] 7 points 11 months ago (1 children)

Thank you for this insight! I will stop eating immediately and die looking like I've barely aged from today.

[–] [email protected] 1 points 11 months ago

This is the way! The key of being young is to not get old!

[–] [email protected] 1 points 11 months ago (1 children)

If eating makes people older I am ancient

[–] [email protected] 0 points 11 months ago (1 children)

It's the function of metabolism that makes us age, the process of living.

So yes, processing food is a key part what uses us and makes us ahe. That doesn't mean people should stop eating, which seems to be a hard concept to grasp.

[–] [email protected] 2 points 11 months ago (1 children)

That doesn't mean people should stop eating, which seems to be a hard concept to grasp.

Damn, you should edit your original comment and put that in, I haven't eaten for a whole 30 minutes now since I read your comment!

This is really difficult to grasp, almost as difficult to grasp as the concept of a joke.

Actually to be serious for a second, I thought restricting how much you ate was proven to slow aging but obviously not stopping eating entirely.

[–] [email protected] 3 points 11 months ago

Ha ha yeah, sometimes I misread the tongue in cheek for irony I guess :-)

Intermittent fasting makes wonders for short lived animals, extending both their lifespan, but, also as important, their health span.

In longer living animals, like humans, it can make a longer health span, mostly if you're overweight or a couch potato. Maybe more, there are studies but they are hard to do and obviously takes a long time for long lived animals. It won't affect a normal lifespan.

[–] [email protected] 3 points 11 months ago (1 children)

This is fascinating research. I'm middle aged now, and hope I gain the benefit of treatments like this!

[–] [email protected] 14 points 11 months ago (1 children)

You won't be able to afford it.

[–] [email protected] 5 points 11 months ago

Did you just assume my financial status?!

(you're probably right)

[–] [email protected] 2 points 11 months ago

Incredible!

We are literally in a Jetsons episode sometimes