Limited cell-autonomous anticancer mechanisms in long-lived bats (www.nature.com)

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Several bat species live >20–40 years, suggesting that they possess efficient anti-aging and anti-cancer defenses.

We hypothesize that some bat species have evolved enhanced p53 activity as an additional anti-cancer strategy, similar to elephants. Further, the absence of unique cell-autonomous tumor suppressive mechanisms may suggest that in vivo bats may rely on enhanced immunosurveillance.

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this post was submitted on 09 Jun 2025

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