• The episode title refers to the hip hop group, A Tribe Called Quest, which Data mentioned as being his favourite recording artists in the TNG episode, “Family”.
• Tribbles first appeared in “The Trouble with Tribbles”.
• Rok-Tahk refers to the tribble by it’s scientific name, tribleustus ventricosus, which was first mentioned in the short, “The Trouble with Edward”.
• Keiko O’Brien’s classroom in DS9 had a diagram of tribble labeled polygeminus grex, which was taken from the “Star Fleet Medical Reference Manual”, published in 1977.
• ”A tribble outbreak once brought the Klingon Empire to its knees.” Worf mentioned in “Trials and Tribble-ations” that tribbles were once considered mortal enemies of the Empire.
• ”But tribbles don’t have teeth.” We saw a tribble with teeth in the PIC episode, “The Bounty”, but that was genetically modified.
• Giant tribbles approaches the Protogies and Chakotay. In the TAS episode, “More Tribbles, More Troubles”, genetically modified tribbles were able to combine together in one large colony creature.
• Doctor K'ruvang is on the planet researching a way for the Klingon Empire to defeat the tribbles. In "More Tribbles, More Troubles" the Klingons had genetically engineered a creature called a glommer to eat tribbles.
• K’ruvang was sent to this planet by Martok, whom we last saw in either “What You Leave Behind”, or “The Least Dangerous Game”, depending on if you count an unlicensed Ferengi boardgame using his likeness.
• Chakotay askes how smart Rok-Tahk actually is, and Dal claims she fixed a core breach in 10 minutes, though he neglected to add that from Rok’s perspective in “Amok Time”, she had significantly more time, perhaps even years.
• Rok accidentally combining her DNA with that of a tribble resulted in a monstrosity. Edward Larkin also combined mixed his DNA into the tribbles in “The Trouble with Edward”.
• Dal mentions that like Rok-Tahk’s abomination, he too is a hybrid being created through combining the DNA of multiple species, as we learned in “Masquerade”.
• Quadrotriticale grain was introduced in “The Trouble With Tribbles”. Though in “More Tribbles, More Troubles”, Starfleet had developed quintotriticale grain.