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Most hand sanitizers use alcohol, which kills indiscriminately. It would kill us if we didn't have livers to filter it, and in high enough doses will kill anyway. Some germs survive due to randomly being out of contact, in nooks and crannies and such, not due to any mechanism that might be selected for.
Answered by /u/ConflagWex
Let's say you throw 1000 humans into a volcano. One of them happens to land on a ledge inside the volcano and escapes. If he has kids, they will not be volcano resistant.
Reply by /u/entenkin