The speech he makes while you climb the citadel is my favourite.
Tell me, Dr. Freeman, if you can: you have destroyed so much — what is it exactly that you have created? Can you name even one thing?... I thought not.
I have laid the foundation for humanity's survival, and not as we have narrowly defined ourselves but as something greater than we could ever imagine, something that we can now only begin to glimpse.
Look, Gordon, look at what you are throwing away. Is it worth it?
As if Gordon hasn't spent the past coupla days (from his perspective) wading through the destruction that the combine has wrought on earth in order to strip it of useful materials.