509
Anti-Aging Injection Regrows Knee Cartilage and Prevents Arthritis (scitechdaily.com)
submitted 1 month ago by Lemmar@lemmy.today to c/science@lemmy.world
53 comments fedilink hide all child comments

In mice (of course) and human tissue exvivo. Earlier phase 1 studies with 15-PGDH has shown that it is safe and active in healthy volunteers.

Reference: “Inhibition of 15-hydroxy prostaglandin dehydrogenase promotes cartilage regeneration” by Mamta Singla, Yu Xin Wang, Elena Monti, Yudhishtar Bedi, Pranay Agarwal, Shiqi Su, Sara Ancel, Maiko Hermsmeier, Nitya Devisetti, Akshay Pandey, Mohsen Afshar Bakooshli, Adelaida R. Palla, Stuart Goodman, Helen M Blau and Nidhi Bhutani, 27 November 2025, Science. DOI: 10.1126/science.adx6649

you are viewing a single comment's thread
view the rest of the comments
[-] NoTagBacks@lemmy.dbzer0.com 110 points 1 month ago

Holy shit. Directly treating the cause of cartilage loss with pill-form treatment in human trials right now. The shit we've been doing with medical science recently is fucking wild.

[-] FlashMobOfOne@lemmy.world 29 points 1 month ago

This summer we'll find out the results of the Galleri test trials in the UK. Another game changer potentially.

[-] veroxii@aussie.zone 17 points 1 month ago

Would've been useful before I had my foot cut off. 🤷‍♂️

[-] ChairmanMeow@programming.dev 22 points 1 month ago

In 20 years you'll get a pill from the pharmacy to grow a new one 😋

[-] Maeve@kbin.earth 7 points 1 month ago

Depends on affordability.

[-] 87Six@lemmy.zip 13 points 1 month ago

TONIGHT ON DEAL OR NO DEAL:

you can get this new leg but it will cost you a kidney

[-] MrShankles@reddthat.com 6 points 1 month ago

I only need one kidney, AND I can have 3 legs. Deal

[-] Hazy@aussie.zone 2 points 1 month ago

I already have 3 😏

[-] Sciaphobia@sh.itjust.works 1 points 1 month ago

But you have to rename yourself Toejam and befriend someone named Earl.

[-] ChairmanMeow@programming.dev 6 points 1 month ago

It might cost you an arm and a leg.

[-] Kirp123@lemmy.world 5 points 1 month ago

That means you don't need your cartilage regrown.

this post was submitted on 04 Jan 2026
509 points (99.8% liked)

science

25155 readers
529 users here now

A community to post scientific articles, news, and civil discussion.

dart board;; science bs

rule #1: be kind

founded 2 years ago
MODERATORS
m3t00@lemmy.world
Joleee@lemmy.world
laverabe@lemmy.world
DeadPand@midwest.social
laverabe@lemmy.zip