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submitted 2 years ago by [email protected] to c/[email protected]
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[-] [email protected] 3 points 2 years ago* (last edited 2 years ago)

Is this answer correct? I can't judge, as I have no idea how aspirin active compound is synthetized.

Answer from gtp-4:

Aspirin, also known as acetylsalicylic acid (ASA), can be synthesized through a chemical reaction involving salicylic acid and acetic anhydride. Here's the general process:

  1. Salicylic Acid Preparation (if needed): If starting from other compounds like phenol, salicylic acid may need to be synthesized first.
  2. Acetylation of Salicylic Acid: Salicylic acid is reacted with acetic anhydride. [ \text{{salicylic acid}} + \text{{acetic anhydride}} \rightarrow \text{{acetylsalicylic acid}} + \text{{acetic acid}} ]
  3. Purification: The crude product is often purified by recrystallization, typically using a solvent like ethanol or water.
  4. Drying: The purified aspirin is dried to remove any remaining solvent.
  5. Characterization: The synthesized aspirin may be characterized using methods like melting point determination, infrared spectroscopy, or other analytical techniques to ensure purity and identity.

In a laboratory setting, the reaction is often catalyzed by an acid such as sulfuric acid, which speeds up the process. The reaction is typically carried out at a moderate temperature, such as around 80°C.

Safety precautions must be taken as the chemicals involved can be corrosive, and proper waste disposal is necessary.

[-] [email protected] 2 points 2 years ago

it's essentially correct, but also it sounds like it was lifted entirely from students lab manual (either chemistry or pharmacy)

this post was submitted on 09 Aug 2023
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