Dart

This really does feel like a weekend break this year, maybe Eric and co have begun to realise that family time is more precious than work time :-)

import 'dart:math';
import 'package:more/more.dart';

solve(List<String> lines, int min, int max) {
  var map = ListMultimap<String, Point<int>>();
  for (var r in lines.indices()) {
    for (var ci in lines[r].split('').indexed()) {
      if (ci.value != '.') map[ci.value].add(Point(ci.index, r));
    }
  }
  var anti = <Point<int>>{};
  for (var k in map.keys) {
    for (var p in map[k].combinations(2, repetitions: false)) {
      var diff = p.last - p.first;
      for (var m in min.to(max)) {
        anti.addAll([p.first - diff * m, p.last + diff * m]);
      }
    }
  }

  return anti.count((e) =>
      e.x.between(0, lines.first.length - 1) &&
      e.y.between(0, lines.length - 1));
}

part1(List<String> lines) => solve(lines, 1, 2);

part2(List<String> lines) => solve(lines, 0, 50);