Chell can't be deaf. On two occasions Wheatley asks her to turn around while he does his thing and waits for her to comply, and the clue to the final boss is delivered through an audio recording.
Final boss
Cave Johnson says that portal-able surfaces are covered in lunar regolith. It's not mentioned anywhere else, and nothing hints at being able to put a portal on the moon.
Of course I'm ignoring the excellent player training integrated into the game's design, but the OOP is ignoring the player (probably) not being deaf and considering only the in-game events.