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submitted 4 months ago* (last edited 1 day ago) by [email protected] to c/[email protected]

The focus of this discussion is the impact on ketones, even in the presence of a high carbohydrate diet. i.e. as a drug people consume.

It is a really interesting area of research. A metabolite can function like a epigenetic drug

https://youtu.be/QJEdToMDWZw

25% of these trails are just using supplementation, not dietary interventions.

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Ketone Metabolic Therapy – Applications, Methods, and Biomarker Monitoring - Dom D'Agostino - #CoSci

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Dr. Dominic D'Agostino discusses ketone metabolic therapy, its applications in health optimization, and monitoring biomarkers. He highlights the research and potential therapeutic benefits of exogenous ketones across various medical contexts, including neurological disorders and metabolic health.

Key Points

Introduction to Ketone Metabolic Therapy

Dr. D'Agostino introduces his research on ketone metabolic therapy, discussing its history, funding sources, and importance in nutritional strategies for health and military resilience.

Applications and Benefits

The talk emphasizes the diverse applications of ketone therapy, including its anti-seizure properties, neuroprotective effects, and potential for enhancing metabolic health, with various studies cited throughout.

Lipid Lowering Experiments

Experiments are discussed regarding lipid-lowering strategies using drugs and lifestyle modifications, focusing on the effects of ketones and dietary changes on LDL and cardiovascular health.

Biomarker Monitoring

The importance of monitoring biomarkers such as blood pressure, glucose, and insulin during ketogenic therapy is highlighted. Dr. D'Agostino shares personal experiences and tools for self-monitoring.

Emerging Research and Trials

D'Agostino reviews recent clinical trials focusing on ketone supplementation for various disorders, outlining the exciting potential for these therapies in treating conditions like Alzheimer's and Parkinson's.

Different Types of Ketone Supplements

The video explores the types of ketone supplements available, their methods of action, and their roles in achieving and maintaining therapeutic ketosis without strict dietary restrictions.

Future Directions in Research

Dr. D'Agostino concludes with thoughts on the future of metabolic therapies, stressing the need for ongoing research and individual monitoring to optimize health outcomes.

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[-] [email protected] 1 points 4 months ago* (last edited 1 day ago)

Major biomakers of interest

Blood Pressure

Blood Glucose

Insulin

Hemoglobin A1C

Uric Acid

High sensitivity CRP

Vitamin B12

Triglycerides, HDL, and ApoB

I do wonder if there is a over focus on chasing metrics in this presenters personal health journey..

this post was submitted on 12 Jan 2025
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Metabolic Health

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