Me personally? I've become much less tolerant of sexist humor. Back in the day, cracking a joke at women's expense was pretty common when I was a teen. As I've matured and become aware to the horrific extent of toxicity and bigotry pervading all tiers of our individualistic society, I've come to see how exclusionarly and objectifying that sort of 'humor' really is, and I regret it deeply.
I honestly don't think it's ableism. Languages evolve and retarded doesn't mean a mental condition it literally means "dumb". Most people don't even know "lame" is related to a movement conditions and if you did a statistical analysis 99% of use cases are not related to the "original meaning". People are just ignorant of how language works, especially since English is a global language.