I think the show has some decent themes that connect together alright. There's a bit of a free will vs determinism thing going on. A bit of what is a human/transporter problem with the robot, the emperor clones, and Harry's mind copies.
But there's also a lot of other noise that kinda makes the show too unfocused to properly explore those ideas. There's some war on terror/fall of Rome imagery. There's the weird religious stuff around the Church of Seldon. The mentalists wanting to put their leader into Gale's body, etc.