100% when. I've learned that the hard way too many times to count at this point...

My NAS is built into an (I think) Thermaltake mid-sized tower running consumer hardware (ASRock X570 Phantom Gaming 4, Ryzen 5 series G proc, G.Skill non-ecc RAM) with the exception of one hard drive. Both that and my proxmox host are repurposed or custom built towers.

I do still use the QNAP NAS too, though only as SMB for my desktop/NFS for my server.