N64 could be done before with overclocking by the looks of it, so this should handle it as a baseline.

Although nothing really gets you over the "our games are in 3D and we don't really know what we're doing" jank of the PS1 and N64 era.

Considering single core performance was the main thing holding it back previously. There is a good chance Nintendo 64 emulation should be better. Other Arm based SBC have been able to do it relatively easily for a while.