I don't know what you're looking to hear, mate. Drawbacks.... a lot of idiots think they are doing science by googling shit when they don't understand science at all. That's not science's fault though, it's the idiots.

Um... when a researcher uncovers something that runs contrary to established science, they are more likely to be met with derision then curiosity. But sometimes researchers are idiots, too, and their science is self-evidently wrong. That's why we have peer review rather than popular review.

Basically science is nothing but upside, however the people attempting it are sometimes flawed. And disproving a hypothesis isn't celebrated enough. Finding out what you thought was so isn't is useful information.