When I work from home, I avoid:

• Unnecessary small talk when making coffee.
• Getting ambushed at my desk and getting cornered into an impromptu meeting.
• Spending close to 2 hours driving that I can spend working instead.
• Being exhausted from having to get up early in the morning.

Literally the only downside is lack of socializing, which depending on the person, isn’t a bad thing. My coworker and I solve that by meeting every other Wednesday at the office for a couple of hours.