Idk, I like the thought of spidermom but they might have 1000 spider babies clinging to her and when they are ready to leave without getting eaten they will all bite her at the same time to stun her while they scatter in all directions and hide in tiny cracks. With how bad the incredibles 2 was I could see them thinking this would be a good idea for incredibles 3.

Alternatively, Pixar is good at telling what if (insert thing) had feelings stories so they'd probably write a pretty dope story about spiders having feelings that makes me question my life choices and makes me feel unreasonably sad about an imaginary creature that says things like "take her to the moon for me".