There is a TV series called The Dropout where Amanda Seyfried plays Elizabeth Holmes and won an award for it. I haven't seen it yet but the trailers don't seem to be able to capture how crazy she seems (like Seyfried seems to be the crazy we're used to seeing; Holmes has a different type of unsettlingness) ... not taking away from Seyfried but Jennifer Lawrence declined or backed out playing Holmes in a movie saying Seyfried's role was enough for this portrayal.

Also, Holmes was saying how none of them were actually playing "her" they were playing an invention she made up ...