People beat horses on the regular. The "man vs horse" race balances the course to try to make it equal. Horses will trounce people on courses under 3 hours or so. Humans do better with steep terrain. So humans will crush a trail endurance race over longer distances. We will lose badly on short, flat courses.

Interestingly dogs are the other species that can really hang with people in endurance runs. We will eventually leave them behind as well. They can outrun us in sprints and courses under a few hours. They can't keep pace at 4+ hours.